Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases

3D printing has opened new opportunities for the development of personalized systems for prosthetics of extensive chest wall defects after radical surgical interventions for malignant tumors. However, risk factors for an adverse outcome of such operations have not yet been identified.Clinical cases....

Full description

Saved in:
Bibliographic Details
Main Authors: A. K. Valiev, P. V. Kononets, T. K. Kharatishvili, A. G. Salkov, N. S. Petrochenko, A.  R. Shin, A. V. Sytov, O. Efimenko
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2023-07-01
Series:Сеченовский вестник
Subjects:
Online Access:https://www.sechenovmedj.com/jour/article/view/941
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849248469708963840
author A. K. Valiev
P. V. Kononets
T. K. Kharatishvili
A. G. Salkov
N. S. Petrochenko
A.  R. Shin
A. V. Sytov
O. Efimenko
author_facet A. K. Valiev
P. V. Kononets
T. K. Kharatishvili
A. G. Salkov
N. S. Petrochenko
A.  R. Shin
A. V. Sytov
O. Efimenko
author_sort A. K. Valiev
collection DOAJ
description 3D printing has opened new opportunities for the development of personalized systems for prosthetics of extensive chest wall defects after radical surgical interventions for malignant tumors. However, risk factors for an adverse outcome of such operations have not yet been identified.Clinical cases. A 65-year-old man with primary chondrosarcoma of the V rib, underwent surgical resection of three ribs, plasty with local tissues, and an individual 3D printed titanium implant was installed on the sternum and IV-VI ribs. Follow up for 26 months showed no complaints or signs of recurrence. A 52-year-old woman with radiation-induced soft tissue sarcoma of the chest wall, that developed 9 years after radiation for breast cancer, underwent resection of four ribs and pectoral muscles and a 3D printed titanium implant was installed on the sternum and II-V ribs. The operation was complicated by the marginal necrosis of the soft tissue flap and infection of the endoprosthesis, which required removal of the metal structure and reconstruction using TRAM flap. After 9 months, a local recurrence of the tumor was diagnosed. Discussion. As a factor of a positive outcome in a man should be noted a thick layer of subcutaneous fat with muscle tissue, due to which plastic surgery was performed, covering the defect without tension. An extensive resection of the pectoral muscles in a woman created a tissue deficit. Another factor of an unfavorable outcome can be considered the radio-induced nature of the sarcoma. Further research is needed to improve the strategy for selecting patients with malignant tumors of the chest wall for prosthetics.
format Article
id doaj-art-62d2f2b2fa4a443f86da4c677ecfbf33
institution Kabale University
issn 2218-7332
2658-3348
language Russian
publishDate 2023-07-01
publisher Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
record_format Article
series Сеченовский вестник
spelling doaj-art-62d2f2b2fa4a443f86da4c677ecfbf332025-08-20T03:57:51ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482023-07-01142576610.47093/2218-7332.2023.14.2.57-66573Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical casesA. K. Valiev0P. V. Kononets1T. K. Kharatishvili2A. G. Salkov3N. S. Petrochenko4A.  R. Shin5A. V. Sytov6O. Efimenko7N.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyN.N. Blokhin National Medical Research Center of OncologyLLC “TIOS”; Samara State Medical University3D printing has opened new opportunities for the development of personalized systems for prosthetics of extensive chest wall defects after radical surgical interventions for malignant tumors. However, risk factors for an adverse outcome of such operations have not yet been identified.Clinical cases. A 65-year-old man with primary chondrosarcoma of the V rib, underwent surgical resection of three ribs, plasty with local tissues, and an individual 3D printed titanium implant was installed on the sternum and IV-VI ribs. Follow up for 26 months showed no complaints or signs of recurrence. A 52-year-old woman with radiation-induced soft tissue sarcoma of the chest wall, that developed 9 years after radiation for breast cancer, underwent resection of four ribs and pectoral muscles and a 3D printed titanium implant was installed on the sternum and II-V ribs. The operation was complicated by the marginal necrosis of the soft tissue flap and infection of the endoprosthesis, which required removal of the metal structure and reconstruction using TRAM flap. After 9 months, a local recurrence of the tumor was diagnosed. Discussion. As a factor of a positive outcome in a man should be noted a thick layer of subcutaneous fat with muscle tissue, due to which plastic surgery was performed, covering the defect without tension. An extensive resection of the pectoral muscles in a woman created a tissue deficit. Another factor of an unfavorable outcome can be considered the radio-induced nature of the sarcoma. Further research is needed to improve the strategy for selecting patients with malignant tumors of the chest wall for prosthetics.https://www.sechenovmedj.com/jour/article/view/9413d printingindividual implantadditive technologiestitanium implantchondrosarcoma of the ribradiation-induced soft tissue sarcoma
spellingShingle A. K. Valiev
P. V. Kononets
T. K. Kharatishvili
A. G. Salkov
N. S. Petrochenko
A.  R. Shin
A. V. Sytov
O. Efimenko
Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
Сеченовский вестник
3d printing
individual implant
additive technologies
titanium implant
chondrosarcoma of the rib
radiation-induced soft tissue sarcoma
title Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
title_full Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
title_fullStr Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
title_full_unstemmed Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
title_short Personalized 3D printed implants in the treatment of extensive chest wall tumors: clinical cases
title_sort personalized 3d printed implants in the treatment of extensive chest wall tumors clinical cases
topic 3d printing
individual implant
additive technologies
titanium implant
chondrosarcoma of the rib
radiation-induced soft tissue sarcoma
url https://www.sechenovmedj.com/jour/article/view/941
work_keys_str_mv AT akvaliev personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT pvkononets personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT tkkharatishvili personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT agsalkov personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT nspetrochenko personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT arshin personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT avsytov personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases
AT oefimenko personalized3dprintedimplantsinthetreatmentofextensivechestwalltumorsclinicalcases