A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose
This study was conducted to determine chloramphenicol level and its clearance time from milk cow with mastitis, which were medicated with chloramphenicol at therapeutic doses.<p> In this experimental study, three groups that each has two Browns Swiss cows were used. Milk samples were collected...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
|
| Series: | Eurasian Journal of Veterinary Sciences |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=749 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841564786142216192 |
|---|---|
| author | Ahmet Acet Ömer Demet D. Ali Dinç Bünyamin Traş A. Levent Baş |
| author_facet | Ahmet Acet Ömer Demet D. Ali Dinç Bünyamin Traş A. Levent Baş |
| author_sort | Ahmet Acet |
| collection | DOAJ |
| description | This study was conducted to determine chloramphenicol level and its clearance time from milk cow with mastitis, which were medicated with chloramphenicol at therapeutic doses.<p>
In this experimental study, three groups that each has two Browns Swiss cows were used. Milk samples were collected and analysed in the last of 1., 2., 3., 4., 5., 6., 7., 8., 12., 24., 32., 46, hours after administration of drug. In Group I, after intramuscular enjection of 10 mg/kg chloramphenicol average drug levels were found as 24.072 mg/kg at first hour, 0.096 mg/kg at eight hour. These levels were 488.720 mg / kg at first 0.19 mg/ kg at twentyfourth hour in Group II after intra-mammar injection 2 g chloramphenicol and 784.05 mg/kg at first, 0.038 mg/kg at thirtysecond in Group III after administration of intramuscular 10 mg/kg intramammar 2 g chloramphenicol combination. No Drug residue was found in milk collected after 8 hour in Group I, 24 hour in Group II and 32 hour in Group III. The curve of chloramphenicol level was showed with a graphic against time period. As a result, chloramphenicol levels and discarding time were seen changing according to administration ways and doses. |
| format | Article |
| id | doaj-art-62cd17e662fb4762a2ab29e6d70d56b3 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-62cd17e662fb4762a2ab29e6d70d56b32025-01-02T22:35:07ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953816163749A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic doseAhmet Acet0Ömer Demet1D. Ali Dinç2Bünyamin Traş3A. Levent Baş4Doç. Dr. İ.Ü. Tıp Fak. Farmakoloji Anabİlim Dalı / MalatyaDoç. Dr. S.Ü. Vat Fak. Farmakoloji Anabilim Dalı / KonyaDoç. Dr. S.Ü. Vat Fak. Doğum ve Rep. Hast Anablllm Dalı / KonyaYrd. Doç. Dr. S.Ü. Vat Fak. Farmakoloji ve Toksikoloji Anabilim Dalı /KonyaArş. Gör. S.Ü. Vat Fak. Farmakoloji ve Toksikoloji Anabilim Dalı / KonyaThis study was conducted to determine chloramphenicol level and its clearance time from milk cow with mastitis, which were medicated with chloramphenicol at therapeutic doses.<p> In this experimental study, three groups that each has two Browns Swiss cows were used. Milk samples were collected and analysed in the last of 1., 2., 3., 4., 5., 6., 7., 8., 12., 24., 32., 46, hours after administration of drug. In Group I, after intramuscular enjection of 10 mg/kg chloramphenicol average drug levels were found as 24.072 mg/kg at first hour, 0.096 mg/kg at eight hour. These levels were 488.720 mg / kg at first 0.19 mg/ kg at twentyfourth hour in Group II after intra-mammar injection 2 g chloramphenicol and 784.05 mg/kg at first, 0.038 mg/kg at thirtysecond in Group III after administration of intramuscular 10 mg/kg intramammar 2 g chloramphenicol combination. No Drug residue was found in milk collected after 8 hour in Group I, 24 hour in Group II and 32 hour in Group III. The curve of chloramphenicol level was showed with a graphic against time period. As a result, chloramphenicol levels and discarding time were seen changing according to administration ways and doses.http://eurasianjvetsci.org/pdf.php3?id=749 |
| spellingShingle | Ahmet Acet Ömer Demet D. Ali Dinç Bünyamin Traş A. Levent Baş A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose Eurasian Journal of Veterinary Sciences |
| title | A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| title_full | A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| title_fullStr | A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| title_full_unstemmed | A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| title_short | A study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| title_sort | study on the levels and withdrawal times of chloramphenicol from milk of mastitic cows medicated with chloramphenicol at therapeutic dose |
| url | http://eurasianjvetsci.org/pdf.php3?id=749 |
| work_keys_str_mv | AT ahmetacet astudyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT omerdemet astudyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT dalidinc astudyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT bunyamintras astudyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT aleventbas astudyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT ahmetacet studyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT omerdemet studyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT dalidinc studyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT bunyamintras studyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose AT aleventbas studyonthelevelsandwithdrawaltimesofchloramphenicolfrommilkofmastiticcowsmedicatedwithchloramphenicolattherapeuticdose |