Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression

Objective(s): The aim of this study is to investigate the possible role of the hippocampal BDNF-PI3K-AKT signaling pathway in the antidepressant-like activity of ellagic acid (EA) in mice.Materials and Methods: Male BALB/C mice were divided into 5 groups; vehicle (0.1 ml/day), sertraline (5mg/kg), E...

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Bibliographic Details
Main Authors: Aslı Bedel, Coskun Usta
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-04-01
Series:Iranian Journal of Basic Medical Sciences
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Online Access:https://ijbms.mums.ac.ir/article_25442_2beeb3acd38aa527a354777818097ba7.pdf
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