Developing a ceRNA-based lncRNA-miRNA-mRNA regulatory network to uncover roles in skeletal muscle development

Developing a ceRNA-based lncRNA-miRNA-mRNA regulatory network to uncover roles in skeletal muscle development

The precise role of lncRNAs in skeletal muscle development and atrophy remain elusive. We conducted a bioinformatic analysis of 26 GEO datasets from mouse studies, encompassing embryonic development, postnatal growth, regeneration, cell proliferation, and differentiation, using R and relevant packag...

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Bibliographic Details
Main Authors: Wang Wenlun, Yu Chaohang, Huang Yan, Li Wenbin, Zhou Nanqing, Hu Qianmin, Wu Shengcai, Yuan Qing, Yu Shirui, Zhang Feng, Zhu Lingyun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Bioinformatics
Subjects:
lncRNA
muscle development and regeneration
cell proliferation and differentiation
muscle atrophy
ceRNA network
signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2024.1494717/full
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