Precision in 3D: A Fast and Accurate Algorithm for Reproducible Motoneuron Structure and Protein Expression Analysis

Precision in 3D: A Fast and Accurate Algorithm for Reproducible Motoneuron Structure and Protein Expression Analysis

Structural analysis of motoneuron somas and their associated proteins via immunohistochemistry (IHC) remains tedious and subjective, requiring costly software or adapted 2D manual methods that lack reproducibility and analytical rigor. Yet, neurodegenerative disease and aging research demands precis...

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Bibliographic Details
Main Authors: Morgan Highlander, Shelby Ward, Bradley LeHoty, Teresa Garrett, Sherif Elbasiouny
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Bioengineering
Subjects:
motoneuron
volumetric analysis
structural analysis
protein expression
Online Access:https://www.mdpi.com/2306-5354/12/7/761
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