Decreased frequency and inflammatory change of FoxP3+ regulatory T cells in immunopathogenesis of human acute graft-versus-host disease

Decreased frequency and inflammatory change of FoxP3+ regulatory T cells in immunopathogenesis of human acute graft-versus-host disease

Background/Aims Acute graft-versus-host disease (GvHD) is a severe complication of allogeneic stem cell transplantation, characterized by immune-mediated tissue damage primarily affecting the skin, liver, and gastrointestinal tract. Regulatory T (Treg) cells play a critical role in maintaining immun...

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Bibliographic Details
Main Authors:	Nayeon Seong, Cheongin Yang, Kunye Kwak, Ka-Won Kang, Yong Park, Byung Soo Kim, Seong Hyun Jeong, Joon Seong Park, Yoon Seok Choi
Format:	Article
Language:	English
Published:	The Korean Association of Internal Medicine 2025-07-01
Series:	The Korean Journal of Internal Medicine
Subjects:	hematopoietic stem cell transplantation graft-versus-host disease regulatory t cell tnf-alpha inflammation
Online Access:	http://kjim.org/upload/kjim-2025-010.pdf
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