Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal

Fungal diseases pose a major threat to global agriculture, leading to reduced crop yields, health issues and significant economic impact. Application of nanoparticles are being explored in agriculture because of its ecofriendly as well as enhanced antimicrobial properties. In this study, using an aq...

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Main Authors: Bimala Subba, Ganga Bir Rai, Rashmi Bhandary, Puja Parajuli, Niru Thapa, Dharma Raj Kandel, Sushika Mulmi, Sabita Shrestha, Sailesh Malla
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024162299
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author Bimala Subba
Ganga Bir Rai
Rashmi Bhandary
Puja Parajuli
Niru Thapa
Dharma Raj Kandel
Sushika Mulmi
Sabita Shrestha
Sailesh Malla
author_facet Bimala Subba
Ganga Bir Rai
Rashmi Bhandary
Puja Parajuli
Niru Thapa
Dharma Raj Kandel
Sushika Mulmi
Sabita Shrestha
Sailesh Malla
author_sort Bimala Subba
collection DOAJ
description Fungal diseases pose a major threat to global agriculture, leading to reduced crop yields, health issues and significant economic impact. Application of nanoparticles are being explored in agriculture because of its ecofriendly as well as enhanced antimicrobial properties. In this study, using an aqueous extract of air-dried tea leaves, zinc oxide nanoparticles (ZnO NPs) are synthesized and it was characterized using various techniques such as X-ray diffraction, UV–Vis, FTIR spectroscopy and microscopic analysis. The growth inhibition activity of the ZnO-NPs was investigated against a phytopathogenic fungus, which was isolated and identified as Fusarium equiseti from tomato plant leaves. Our result showed that application of ZnO NPs at 750 ppm–1200 ppm concentration range inhibited the growth of F. equiseti by 77.6 %–85.1 % at 7 days of seeding the fungi in PDA media. Microscopic observation of the fungal strain treated with ZnO NPs showed that the presence of the nanoparticles agglomerates the normal hyphae of F. equiseti and formed curve tips and breakage of mycelia. Hence, our study shows that application ZnO NPs is promising approach for fungal growth inhibition and can be deployed to inhibit other plant diseases causing microbes in agriculture.
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institution Kabale University
issn 2405-8440
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spelling doaj-art-615173f8bd0d44149a7949b93b77d0442024-11-30T07:12:04ZengElsevierHeliyon2405-84402024-11-011022e40198Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in NepalBimala Subba0Ganga Bir Rai1Rashmi Bhandary2Puja Parajuli3Niru Thapa4Dharma Raj Kandel5Sushika Mulmi6Sabita Shrestha7Sailesh Malla8Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalDepartment of Bionanotechnology and Bioconvergence Engineering, Jeonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju, 54896, Republic of KoreaCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, NepalCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal; Corresponding author.Strain Improvement Department, Microbe and Culture Research, R&D, Novonesis, Hørsholm, DenmarkFungal diseases pose a major threat to global agriculture, leading to reduced crop yields, health issues and significant economic impact. Application of nanoparticles are being explored in agriculture because of its ecofriendly as well as enhanced antimicrobial properties. In this study, using an aqueous extract of air-dried tea leaves, zinc oxide nanoparticles (ZnO NPs) are synthesized and it was characterized using various techniques such as X-ray diffraction, UV–Vis, FTIR spectroscopy and microscopic analysis. The growth inhibition activity of the ZnO-NPs was investigated against a phytopathogenic fungus, which was isolated and identified as Fusarium equiseti from tomato plant leaves. Our result showed that application of ZnO NPs at 750 ppm–1200 ppm concentration range inhibited the growth of F. equiseti by 77.6 %–85.1 % at 7 days of seeding the fungi in PDA media. Microscopic observation of the fungal strain treated with ZnO NPs showed that the presence of the nanoparticles agglomerates the normal hyphae of F. equiseti and formed curve tips and breakage of mycelia. Hence, our study shows that application ZnO NPs is promising approach for fungal growth inhibition and can be deployed to inhibit other plant diseases causing microbes in agriculture.http://www.sciencedirect.com/science/article/pii/S2405844024162299PhytopathogenFungiFusarium equisetiGrowth inhibitionTea leavesZnO nanoparticles
spellingShingle Bimala Subba
Ganga Bir Rai
Rashmi Bhandary
Puja Parajuli
Niru Thapa
Dharma Raj Kandel
Sushika Mulmi
Sabita Shrestha
Sailesh Malla
Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
Heliyon
Phytopathogen
Fungi
Fusarium equiseti
Growth inhibition
Tea leaves
ZnO nanoparticles
title Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
title_full Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
title_fullStr Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
title_full_unstemmed Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
title_short Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal
title_sort antifungal activity of zinc oxide nanoparticles zno nps on fusarium equiseti phytopathogen isolated from tomato plant in nepal
topic Phytopathogen
Fungi
Fusarium equiseti
Growth inhibition
Tea leaves
ZnO nanoparticles
url http://www.sciencedirect.com/science/article/pii/S2405844024162299
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