Sperm metabolomic signatures of asthenozoospermia and teratozoospermia in Chinese reproductive-age men

Sperm metabolomic signatures of asthenozoospermia and teratozoospermia in Chinese reproductive-age men

Abstract Asthenozoospermia and teratozoospermia are common causes of male infertility. Despite their prevalence, the underlying metabolic mechanisms remain poorly understood. In this study, we conducted targeted metabolomic profiling of sperm samples from 131 Chinese reproductive-age men (48 normozo...

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Bibliographic Details
Main Authors: Youzhu Li, Zhonghua Lu, Jingu Li, Ling Cheng, Yuanyuan Ye, Song Xu, Junfeng Tan, Lifeng Zheng, Huiyi Xie, Qisheng Zhong, Jiaqi Liu, Yunfan Yang, Rui Guo, Guoshi Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Male infertility
Asthenozoospermia
Teratozoospermia
Metabolome
Sperm
Machine learning
Online Access:https://doi.org/10.1038/s41598-025-09787-1
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