Dissolution of struvite stones with ascorbic acid
This case report describes an elderly man with a history of recurrent urinary tract infections and obstructive pyelonephritis with struvite stones caused by Proteus mirabilis. Despite appropriate antibiotic treatment, the stones increased in size, necessitating alternative therapy. This case highlig...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442024002602 |
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| author | Satoshi Yoshikawa |
| author_facet | Satoshi Yoshikawa |
| author_sort | Satoshi Yoshikawa |
| collection | DOAJ |
| description | This case report describes an elderly man with a history of recurrent urinary tract infections and obstructive pyelonephritis with struvite stones caused by Proteus mirabilis. Despite appropriate antibiotic treatment, the stones increased in size, necessitating alternative therapy. This case highlights the use of ascorbic acid to lower the urine pH, which contributes to the dissolution of struvite stones. Dual-energy CT was used to differentiate the stone composition for the initiation of ascorbic acid. These findings suggest that ascorbic acid can accelerate struvite stone dissolution, and that dual-energy CT is valuable for both initial diagnosis and follow-up. |
| format | Article |
| id | doaj-art-602df4906c40413da30c880bd591dfbc |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-602df4906c40413da30c880bd591dfbc2025-01-14T04:12:20ZengElsevierUrology Case Reports2214-44202025-01-0158102906Dissolution of struvite stones with ascorbic acidSatoshi Yoshikawa0Department of Emergency and General Internal Medicine, Rakuwakai Marutamachi Hospital, 9-7 Jurakumawari-Matsushita-cho, Nakagyo-ku, 604-8401, Kyoto, JapanThis case report describes an elderly man with a history of recurrent urinary tract infections and obstructive pyelonephritis with struvite stones caused by Proteus mirabilis. Despite appropriate antibiotic treatment, the stones increased in size, necessitating alternative therapy. This case highlights the use of ascorbic acid to lower the urine pH, which contributes to the dissolution of struvite stones. Dual-energy CT was used to differentiate the stone composition for the initiation of ascorbic acid. These findings suggest that ascorbic acid can accelerate struvite stone dissolution, and that dual-energy CT is valuable for both initial diagnosis and follow-up.http://www.sciencedirect.com/science/article/pii/S2214442024002602urolithiasiskidney stoneureteral stoneascorbic acidcranberry juiceDual-energy CT |
| spellingShingle | Satoshi Yoshikawa Dissolution of struvite stones with ascorbic acid Urology Case Reports urolithiasis kidney stone ureteral stone ascorbic acid cranberry juice Dual-energy CT |
| title | Dissolution of struvite stones with ascorbic acid |
| title_full | Dissolution of struvite stones with ascorbic acid |
| title_fullStr | Dissolution of struvite stones with ascorbic acid |
| title_full_unstemmed | Dissolution of struvite stones with ascorbic acid |
| title_short | Dissolution of struvite stones with ascorbic acid |
| title_sort | dissolution of struvite stones with ascorbic acid |
| topic | urolithiasis kidney stone ureteral stone ascorbic acid cranberry juice Dual-energy CT |
| url | http://www.sciencedirect.com/science/article/pii/S2214442024002602 |
| work_keys_str_mv | AT satoshiyoshikawa dissolutionofstruvitestoneswithascorbicacid |