Gene expression cluster differences and molecular correlation with the STING pathway in orbital MALT lymphoma and orbital IgG4-related eye disease

Gene expression cluster differences and molecular correlation with the STING pathway in orbital MALT lymphoma and orbital IgG4-related eye disease

Abstract Purpose Mucosa-associated lymphoid tissue (MALT) lymphoma in the orbital region and IgG4-related ophthalmic disease (IgG4-ROD) account for the majority of mass lesions in the orbital region. These diseases may show similar shadows on radiologic images, and many cases are difficult to differ...

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Bibliographic Details
Main Authors: Mizuki Tagami, Keishiro Isayama, Mizuho Nishio, Atsuko Yoshikawa, Norihiko Misawa, Atsushi Sakai, Yusuke Haruna, Mami Tomita, Yoichi Mizukami, Atsushi Azumi, Shigeru Honda
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
RNA-seq
Principal component analysis
IgG4-related ophthalmic disease (IgG4-ROD)
Orbital MALT lymphoma
Machine learning
STING
Online Access:https://doi.org/10.1007/s12672-025-03239-y
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