What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?

The reported links of asthma morbidity and mortality to the use of in haled beta-agonist bronchodilators are reviewed. Reports from the Saskatchewan Asthma Epidemiology Project (SAEP) suggest that it is excessive use that is linked to life-threatening asthma and that patients at highest risk can be...

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Main Author: Pierre Ernst
Format: Article
Language:English
Published: Wiley 1995-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1995/396751
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author Pierre Ernst
author_facet Pierre Ernst
author_sort Pierre Ernst
collection DOAJ
description The reported links of asthma morbidity and mortality to the use of in haled beta-agonist bronchodilators are reviewed. Reports from the Saskatchewan Asthma Epidemiology Project (SAEP) suggest that it is excessive use that is linked to life-threatening asthma and that patients at highest risk can be identified by their increasing use of these medications. This is the major justification for prescribing short acting beta-agonists on an as needed basis, though there is both clinical and experimental evidence suggesting regular use of these agents may not be beneficial. New longer acting inhaled beta-agonists designed for regular use are being introduced and their exact role remains to be defined. Provisionally, they appear to be useful in patients whose asthma is not well controlled with optimal doses of inhaled corticosteroids. The use of these newer agents for the relief of acute bronchospasm is contraindicated because of their slow onset of action.
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spelling doaj-art-601cb93222914e8f8af6e66bc32e376b2025-02-03T05:47:26ZengWileyCanadian Respiratory Journal1198-22411995-01-012Suppl A32A34A10.1155/1995/396751What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?Pierre Ernst0Respiratory Epidemiology Unit, Department of Epidemiology and Biostatistics, and Department of Medicine, McGill University, Asthma Unit, Montreal General Hospital Montreal, Montreal, Quebec, CanadaThe reported links of asthma morbidity and mortality to the use of in haled beta-agonist bronchodilators are reviewed. Reports from the Saskatchewan Asthma Epidemiology Project (SAEP) suggest that it is excessive use that is linked to life-threatening asthma and that patients at highest risk can be identified by their increasing use of these medications. This is the major justification for prescribing short acting beta-agonists on an as needed basis, though there is both clinical and experimental evidence suggesting regular use of these agents may not be beneficial. New longer acting inhaled beta-agonists designed for regular use are being introduced and their exact role remains to be defined. Provisionally, they appear to be useful in patients whose asthma is not well controlled with optimal doses of inhaled corticosteroids. The use of these newer agents for the relief of acute bronchospasm is contraindicated because of their slow onset of action.http://dx.doi.org/10.1155/1995/396751
spellingShingle Pierre Ernst
What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
Canadian Respiratory Journal
title What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
title_full What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
title_fullStr What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
title_full_unstemmed What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
title_short What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?
title_sort what is the role of beta agonist bronchodilators in the day to day treatment of chronic asthma
url http://dx.doi.org/10.1155/1995/396751
work_keys_str_mv AT pierreernst whatistheroleofbetaagonistbronchodilatorsinthedaytodaytreatmentofchronicasthma