Clinical Relevance and Drug Modulation of PPAR Signaling Pathway in Triple-Negative Breast Cancer: A Comprehensive Analysis

Clinical Relevance and Drug Modulation of PPAR Signaling Pathway in Triple-Negative Breast Cancer: A Comprehensive Analysis

Triple-negative breast cancer (TNBC) is highly heterogeneous and poses a significant medical challenge due to limited treatment options and poor outcomes. Peroxisome proliferator-activated receptors (PPARs) play a crucial role in regulating metabolism and cell fate. While the association between PPA...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yanxia Zhang, Yunduo Liu, Mei Zhang, Guanjie Li, Siling Zhu, Keping Xie, Bin Xiao, Linhai Li
Format:	Article
Language:	English
Published:	Wiley 2024-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/ppar/4164906
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Identification of ERBB Pathway-Activated Cells in Triple-Negative Breast Cancer
by: Soo Young Cho
Published: (2019-03-01)

Identifying candidate drugs based on transcriptional landscape associated with triple-negative breast cancer
by: Yuqin Lin, et al.
Published: (2023-12-01)

Characterization of Triple Negative Breast Cancer
by: Bernardo Enrique Heredia Martínez, et al.
Published: (2020-09-01)

Molecular effects of clinically relevant chemotherapeutic agents on choline phospholipid metabolism in triple negative breast cancer cells
by: Caitlin M. Tressler, et al.
Published: (2025-03-01)

The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer
by: Yao Yi, et al.
Published: (2025-01-01)

Tumor microenvironment and immunotherapy for triple-negative breast cancer
by: Zijie Guo, et al.
Published: (2024-12-01)

Advances in the Understanding of the Pathogenesis of Triple‐Negative Breast Cancer
by: Yuhan Liu, et al.
Published: (2024-11-01)

Clinical Characteristics in Patients with Triple Negative Breast Cancer
by: Janet Yeh, et al.
Published: (2017-01-01)

Natural products as part of triple negative breast cancer
by: Yozlem Kobakova, et al.
Published: (2025-01-01)

Triple-Negative Breast Cancer: Tumor Immunogenicity and Beyond
by: Elio Ibrahim, et al.
Published: (2024-01-01)

Classifications of triple-negative breast cancer: insights and current therapeutic approaches
by: Ziqi Chen, et al.
Published: (2025-02-01)

Outcome for Patients with Triple-Negative Breast Cancer Is Not Dependent on Race/Ethnicity
by: Quyen D. Chu, et al.
Published: (2012-01-01)

The overview of modern approaches in treatment of triple negative breast cancer
by: A. A. Kharitonova, et al.
Published: (2020-03-01)

Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy
by: Parvin F. Peddi, et al.
Published: (2012-01-01)

Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment
by: Tangyi Wang, et al.
Published: (2025-01-01)

Targeting ANXA1 abrogates Treg-mediated immune suppression in triple-negative breast cancer
by: Bin Li, et al.
Published: (2020-05-01)

Endothelial Cells Potentially Participate in the Metastasis of Triple-Negative Breast Cancer
by: Yanfei Ma, et al.
Published: (2022-01-01)

Prognostic model based on tumor stemness genes for triple-negative breast cancer
by: Min Ouyang, et al.
Published: (2024-12-01)

Inosine monophosphate dehydrogenase 2 (IMPDH2) modulates response to therapy and chemo-resistance in triple negative breast cancer
by: Tatiane da Silva Fernandes, et al.
Published: (2025-01-01)

Self-propelling, protein-bound magnetic nanobots for efficient in vitro drug delivery in triple negative breast cancer cells
by: Neha Naikwadi, et al.
Published: (2024-12-01)

Targeting PRMT5 through PROTAC for the treatment of triple-negative breast cancer
by: Yaxun Guo, et al.
Published: (2024-11-01)

Synthesis of Zinc Oxide-Doped Carbon Dots for Treatment of Triple-Negative Breast Cancer
by: Wang M, et al.
Published: (2024-12-01)

Unlocking the epigenetic code: new insights into triple-negative breast cancer
by: Gowthami Mahendran, et al.
Published: (2024-12-01)

Metabolic Syndrome and Triple-Negative Breast Cancer: A New Paradigm
by: Andrew A. Davis, et al.
Published: (2012-01-01)

Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
by: Kun Fang, et al.
Published: (2025-01-01)

Identification and validation of neutrophils-related subtypes and prognosis model in triple negative breast cancer
by: Shanqi Li, et al.
Published: (2024-03-01)

Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple‐Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1‐Regulated Cholesterol Metabolism
by: Yilan Yang, et al.
Published: (2025-02-01)

Ketogenesis promotes triple-negative breast cancer metastasis via calpastatin β-hydroxybutyrylation
by: Haoran Jiang, et al.
Published: (2024-11-01)

Enhancement of Doxorubicin Efficacy by Bacopaside II in Triple-Negative Breast Cancer Cells
by: Sima Kianpour Rad, et al.
Published: (2025-01-01)

Transcriptomic analysis reveals potential crosstalk genes and immune relationship between triple-negative breast cancer and depression
by: Zhili Zhuo, et al.
Published: (2024-12-01)

The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer
by: Zheng Xu, et al.
Published: (2025-01-01)

Hyaluronic acid-functionalized supramolecular nanophotosensitizers for targeted photoimmunotherapy of triple-negative breast cancer
by: Haiyan Zhang, et al.
Published: (2024-12-01)

Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
by: Chang Cheng, et al.
Published: (2025-01-01)

Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial–mesenchymal transition in triple-negative breast cancer
by: Xi Chen, et al.
Published: (2024-12-01)

Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Enduring Legacy, Emerging Evidence
by: Wei Peng, et al.
Published: (2024-11-01)

METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer
by: Xupeng Bai, et al.
Published: (2024-11-01)

Platycodon grandiflorum-derived extracellular vesicles suppress triple-negative breast cancer growth by reversing the immunosuppressive tumor microenvironment and modulating the gut microbiota
by: Min Yang, et al.
Published: (2025-02-01)

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway
by: Rumeng Ding, et al.
Published: (2025-01-01)

Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer
by: Yang Cui, et al.
Published: (2024-11-01)

Construction of the bromodomain-containing protein-associated prognostic model in triple-negative breast cancer
by: Wei Chen, et al.
Published: (2025-01-01)