Catalytic peptide-based coacervates for enhanced function through structural organization and substrate specificity

Abstract Liquid-liquid phase separation (LLPS) in living cells provides innovative pathways for synthetic compartmentalized catalytic systems. While LLPS has been explored for enhancing enzyme catalysis, its potential application to catalytic peptides remains unexplored. Here, we demonstrate the use...

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Bibliographic Details
Main Authors: David Q. P. Reis, Sara Pereira, Ana P. Ramos, Pedro M. Pereira, Leonor Morgado, Joana Calvário, Adriano O. Henriques, Mónica Serrano, Ana S. Pina
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53699-z
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