Improving 3D deep learning segmentation with biophysically motivated cell synthesis

Abstract Biomedical research increasingly relies on three-dimensional (3D) cell culture models and artificial-intelligence-based analysis can potentially facilitate a detailed and accurate feature extraction on a single-cell level. However, this requires for a precise segmentation of 3D cell dataset...

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Bibliographic Details
Main Authors: Roman Bruch, Mario Vitacolonna, Elina Nürnberg, Simeon Sauer, Rüdiger Rudolf, Markus Reischl
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07469-2
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