Testing for Endothelial Dysfunction in Children with Rare Genetic Variants of Obesity

Testing for Endothelial Dysfunction in Children with Rare Genetic Variants of Obesity

<b>Background:</b> Endothelial dysfunction (ED), an early indicator of atherosclerosis, is a well-established predictor of cardiovascular disease. This study investigates ED in children with rare genetic variants linked to obesity and explores the prevalence of these variants in pediatri...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ilham Farhat, Vivian L. Chin
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Endocrines
Subjects:	early onset obesity genetic variants endothelial dysfunction pediatric endocrinology RHI reactive hyperemia index
Online Access:	https://www.mdpi.com/2673-396X/5/4/44
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Assessment of Endothelial Function in Patients with COVID-19 Using Peripheral Arterial Tonometry
by: Athanasios Moulias, et al.
Published: (2024-11-01)

Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development
by: Richard L. Jayaraj, et al.
Published: (2025-01-01)

Endothelial dysfunction is an early event in the pathophysiology of obesity
by: Gui-Fen ZHANG, et al.
Published: (2020-10-01)

Whole Exome Sequencing Revealed Paternal Inheritance of Obesity-related Genetic Variants in a Family with an Exclusively Breastfed Infant
by: Hazal Banu Olgun Çelebioğlu, et al.
Published: (2024-12-01)

Tumour-Not So Sweet, Tumour-Induced Hypoglycemia: A Rare Case of Refractory Hypoglycemia in a Toddler
by: Jayati Joshipura, et al.
Published: (2021-12-01)

Increased serum galectin-3 level is associated with endothelial dysfunction and cardiovascular events in patients with hypertension
by: Hui-Sheng Wang, et al.
Published: (2025-01-01)

The relationship of visceral adiposity with endothelial functions and subclinical atherosclerosis in obese individuals
by: Kose Merve Polat, et al.
Published: (2024-12-01)

Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome
by: Nadja Scherbakov, et al.
Published: (2020-06-01)

Peripheral Endothelial Dysfunction Is Associated With Incident Major Depressive Disorder
by: Jaskanwal D. S. Sara, et al.
Published: (2024-11-01)

The impact of prediabetes and diabetes on endothelial function in a large population-based cohort
by: H. Holm, et al.
Published: (2024-12-01)

Novel biallelic variants in IREB2 cause an early-onset neurodegenerative disorder in a Chinese pedigree
by: Zhenglong Guo, et al.
Published: (2024-11-01)

Rare presentation of vitamin D toxicity with hypertriglyceridemia and pancreatitis
by: Bushra Rehman, et al.
Published: (2025-01-01)

Clinical and molecular characterisation of children with monogenic obesity: a case series
by: Arun George, et al.
Published: (2024-07-01)

Endothelial Dysfunction and Cardiovascular Disease: Hyperbaric Oxygen Therapy as an Emerging Therapeutic Modality?
by: Tanja Batinac, et al.
Published: (2024-12-01)

The Effect of Acute Sleep Extension on Blood Pressure Is Dependent on the Change in Sleep Efficiency
by: Joaquin U. Gonzales, et al.
Published: (2024-10-01)

Limb Position Influences Peripheral Arterial Stiffness Reduction with Reactive Hyperemia
by: Ronald E. Jackson, et al.
Published: (2024-07-01)

Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes
by: Yizhen Bai, et al.
Published: (2025-01-01)

The Link Between Venous and Arterial Thrombosis: Is There a Role for Endothelial Dysfunction?
by: Marco Paolo Donadini, et al.
Published: (2025-01-01)

The Impact of Inflammatory Markers and Obesity in Chronic Venous Disease
by: Flavia-Medana Petrascu, et al.
Published: (2024-11-01)

Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease
by: Ana Paula Madariaga Traconis, et al.
Published: (2024-12-01)

Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer’s disease: a neuropsychological data-driven approach
by: Deepti Putcha, et al.
Published: (2025-02-01)

Plasma from hypertensive pregnancy patients induce endothelial dysfunction even under atheroprotective shear stress
by: Sarah Viana-Mattioli, et al.
Published: (2025-02-01)

Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism
by: L. V. Chesnokova, et al.
Published: (2014-12-01)

The extracellular CIRP as a predictive marker for the endothelial dysfunction in chronic obstructive pulmonary disease combined with pulmonary hypertension
by: Yun Yao, et al.
Published: (2024-12-01)

Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling
by: Mandy O. J. Grootaert, et al.
Published: (2025-02-01)

Endothelial activation and dysfunction caused by influenza A virus (<i>Alphainfluenzavirus influenzae</i>)
by: Vladimir A. Marchenko, et al.
Published: (2024-12-01)

Frontotemporal dementia: peculiarities of clinical variants
by: B. Klimbytė, et al.
Published: (2021-12-01)

A structured framework for pediatric endocrine resident rotations: a single center experience
by: Rachel Zipursky, et al.
Published: (2024-12-01)

Nitric oxide role in development of the endothelial dysfunction in diabetic foot syndrome
by: O. O. Bilyayeva, et al.
Published: (2019-12-01)

Angiotensin II Induces Vascular Endothelial Dysfunction by Promoting Lipid Peroxidation-Mediated Ferroptosis via CD36
by: Qian Zhou, et al.
Published: (2024-11-01)

Palmitic Acid Accelerates Endothelial Cell Injury and Cardiovascular Dysfunction via Palmitoylation of PKM2
by: Yu He, et al.
Published: (2025-02-01)

Periodontitis as a risk factor for organic erectile dysfunction: A case-control study in a sub-Saharan population
by: Abdoulaye Diouf, et al.
Published: (2023-12-01)

The Role of Omega-3 Polyunsaturated Fatty Acids in Patients with Metabolic Syndrome and Endothelial Dysfunction
by: Andrej Dzupina, et al.
Published: (2024-12-01)

Endothelial dysfunction in prediabetes and diabetes mellitus in patients with normal coronary arteries
by: Asli Inci Atar, et al.
Published: (2024-11-01)

Comprehensive case report and literature review on perioperative management of multiple pheochromocytoma in a pediatric patient
by: Shenghua Yu, et al.
Published: (2025-02-01)

Pyroptosis in Endothelial Cells and Extracellular Vesicle Release in Atherosclerosis via NF-κB-Caspase-4/5-GSDM-D Pathway
by: Salman Shamas, et al.
Published: (2024-11-01)

Effect of plant-based functional foods for the protection against salt-induced endothelial dysfunction
by: Sheung Yin San, et al.
Published: (2022-09-01)

Targeting Insulin Resistance, Reactive Oxygen Species, Inflammation, Programmed Cell Death, ER Stress, and Mitochondrial Dysfunction for the Therapeutic Prevention of Free Fatty Acid-Induced Vascular Endothelial Lipotoxicity
by: Chong-Sun Khoi, et al.
Published: (2024-12-01)

Significance of single-nucleotide variants of anorexigenic hormone genes in childhood obesity
by: A.O. Nikulina
Published: (2024-04-01)

The impact of perindopril and metformin on the markers of endothelial dysfunction in rats with acute intracerebral hemorrhage and type 2 diabetes mellitus
by: V.I. Zhyliuk, et al.
Published: (2021-12-01)