Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury

Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury

We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury. While exosomes are recognized as playing a pivotal role in neural stem cells exocrine function, their precise function in spinal cord injury remains unclear. To investigate...

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Bibliographic Details
Main Authors: Shiming Li, Jianfeng Li, Guoliang Chen, Tao Lin, Penghui Zhang, Kuileung Tong, Ningning Chen, Shaoyu Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-11-01
Series:Neural Regeneration Research
Subjects:
cellular communication
competing endogenous rna
exosomes
foxp1
necroptosis
neural stem cells
slc16a3
spinal cord injury
transcriptome sequencing
tsc2
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00068
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