MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2

MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2

Abstract Osteoarthritis (OA), the most prevalent degenerative joint disease, is marked by cartilage degradation and pathological alterations in surrounding tissues. Currently, no effective disease-modifying treatments exist. This study aimed to elucidate the critical roles of Myb-like, SWIRM, and MP...

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Bibliographic Details
Main Authors: Kang Wei, Chuankun Zhou, Zixing Shu, Xingru Shang, Yi Zou, Wei Zhou, Huanhuan Xu, Yulin Liang, Tian Ma, Xuying Sun, Jun Xiao
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-024-00368-y
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