Movie-watching evokes ripple-like activity within events and at event boundaries
Abstract Ripples are fast oscillatory events widely recognized as crucial markers for memory consolidation and neural plasticity. These transient bursts of activity are thought to coordinate information transfer between the hippocampus and neocortical areas, providing a temporal framework that suppo...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60788-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849334610793594880 |
|---|---|
| author | Marta Silva Xiongbo Wu Marc Sabio Estefanía Conde-Blanco Pedro Roldán Antonio Donaire Mar Carreño Nikolai Axmacher Christopher Baldassano Lluís Fuentemilla |
| author_facet | Marta Silva Xiongbo Wu Marc Sabio Estefanía Conde-Blanco Pedro Roldán Antonio Donaire Mar Carreño Nikolai Axmacher Christopher Baldassano Lluís Fuentemilla |
| author_sort | Marta Silva |
| collection | DOAJ |
| description | Abstract Ripples are fast oscillatory events widely recognized as crucial markers for memory consolidation and neural plasticity. These transient bursts of activity are thought to coordinate information transfer between the hippocampus and neocortical areas, providing a temporal framework that supports the stabilization and integration of new memories. However, their role in human memory encoding during naturalistic scenarios remains unexplored. Here, we recorded intracranial electrophysiological data from ten epilepsy patients watching a movie. Ripples were analyzed in the hippocampus and neocortical regions (i.e., temporal and frontal cortex). Our results revealed a differential dynamical pattern of ripple occurrence during encoding. Enhanced hippocampal ripple recruitment was observed at event boundaries, reflecting hippocampal involvement in event segmentation, whereas higher ripple rates were seen within an event for cortical electrodes with higher ripple occurrence at the temporal cortex, reflecting whether an event was later recalled. These findings shed light on the neural mechanisms underlying memory encoding and provide insights into the potential role of ripples in the encoding of an event, suggesting an impact on the formation of long-term memories of distinct episodes. |
| format | Article |
| id | doaj-art-5f5af7d8ab9f4b96aa41f1be65ebc13b |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-5f5af7d8ab9f4b96aa41f1be65ebc13b2025-08-20T03:45:31ZengNature PortfolioNature Communications2041-17232025-07-0116111110.1038/s41467-025-60788-0Movie-watching evokes ripple-like activity within events and at event boundariesMarta Silva0Xiongbo Wu1Marc Sabio2Estefanía Conde-Blanco3Pedro Roldán4Antonio Donaire5Mar Carreño6Nikolai Axmacher7Christopher Baldassano8Lluís Fuentemilla9Department of Cognition, Development and Education Psychology, University of BarcelonaDepartment of Psychology, Ludwig-Maximilians-Universität MünchenDepartment of Cognition, Development and Education Psychology, University of BarcelonaDepartment of Neurology, Hospital Clínic de Barcelona, Universitat de BarcelonaDepartment of Neurology, Hospital Clínic de Barcelona, Universitat de BarcelonaDepartment of Neurology, Hospital Clínic de Barcelona, Universitat de BarcelonaDepartment of Neurology, Hospital Clínic de Barcelona, Universitat de BarcelonaDepartment of Neuropsychology, Institute of Cognitive Neuroscience, Faculty of Psychology, Ruhr-Universität BochumDepartment of Psychology, Columbia UniversityDepartment of Cognition, Development and Education Psychology, University of BarcelonaAbstract Ripples are fast oscillatory events widely recognized as crucial markers for memory consolidation and neural plasticity. These transient bursts of activity are thought to coordinate information transfer between the hippocampus and neocortical areas, providing a temporal framework that supports the stabilization and integration of new memories. However, their role in human memory encoding during naturalistic scenarios remains unexplored. Here, we recorded intracranial electrophysiological data from ten epilepsy patients watching a movie. Ripples were analyzed in the hippocampus and neocortical regions (i.e., temporal and frontal cortex). Our results revealed a differential dynamical pattern of ripple occurrence during encoding. Enhanced hippocampal ripple recruitment was observed at event boundaries, reflecting hippocampal involvement in event segmentation, whereas higher ripple rates were seen within an event for cortical electrodes with higher ripple occurrence at the temporal cortex, reflecting whether an event was later recalled. These findings shed light on the neural mechanisms underlying memory encoding and provide insights into the potential role of ripples in the encoding of an event, suggesting an impact on the formation of long-term memories of distinct episodes.https://doi.org/10.1038/s41467-025-60788-0 |
| spellingShingle | Marta Silva Xiongbo Wu Marc Sabio Estefanía Conde-Blanco Pedro Roldán Antonio Donaire Mar Carreño Nikolai Axmacher Christopher Baldassano Lluís Fuentemilla Movie-watching evokes ripple-like activity within events and at event boundaries Nature Communications |
| title | Movie-watching evokes ripple-like activity within events and at event boundaries |
| title_full | Movie-watching evokes ripple-like activity within events and at event boundaries |
| title_fullStr | Movie-watching evokes ripple-like activity within events and at event boundaries |
| title_full_unstemmed | Movie-watching evokes ripple-like activity within events and at event boundaries |
| title_short | Movie-watching evokes ripple-like activity within events and at event boundaries |
| title_sort | movie watching evokes ripple like activity within events and at event boundaries |
| url | https://doi.org/10.1038/s41467-025-60788-0 |
| work_keys_str_mv | AT martasilva moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT xiongbowu moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT marcsabio moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT estefaniacondeblanco moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT pedroroldan moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT antoniodonaire moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT marcarreno moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT nikolaiaxmacher moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT christopherbaldassano moviewatchingevokesripplelikeactivitywithineventsandateventboundaries AT lluisfuentemilla moviewatchingevokesripplelikeactivitywithineventsandateventboundaries |