A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China
ContextThere are limited real-world data evidence assessing the clinical characteristics of hospitalized osteoporotic fractures in China.ObjectiveTo investigate the clinical characteristics of hospitalized major osteoporotic fractures in Northeast China.MethodsWe identified hospitalized fracture pat...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1520229/full |
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| author | Qi Meng Qi Meng Xinwei Wang Yuzhong Gao William D. Leslie Lisa M. Lix Xianbao Shi Bo Kan Shuman Yang Shuman Yang |
| author_facet | Qi Meng Qi Meng Xinwei Wang Yuzhong Gao William D. Leslie Lisa M. Lix Xianbao Shi Bo Kan Shuman Yang Shuman Yang |
| author_sort | Qi Meng |
| collection | DOAJ |
| description | ContextThere are limited real-world data evidence assessing the clinical characteristics of hospitalized osteoporotic fractures in China.ObjectiveTo investigate the clinical characteristics of hospitalized major osteoporotic fractures in Northeast China.MethodsWe identified hospitalized fracture patients aged 50 and over from the First Affiliated Hospital of Jinzhou Medical University between January 1, 2018, and December 31, 2022. Major osteoporotic fractures including hip, vertebral, forearm and wrist, and humerus were diagnosed based on x-ray reports extracted from the electronic medical records (EMR). The cause of fracture, comorbidities, surgical methods, and anti-osteoporotic medications (AM) use were extracted from EMR.ResultsThe study population included 1823 fracture patients, 510 males and 1313 females. Over half of fracture patients were aged over 70 years. Hip fractures accounted for 68.4% of all fractures in males and 57.9% in females. For those with hip fractures, the most common sites were the femoral neck (62.9%) and intertrochanteric (35.3%). Most fractures were due to falls (81.0% in males and 80.2% in females). The two most common comorbidities for males and females were hyperlipemia (45.9% vs. 47.1%) and hypertension (38.2% vs. 41.6%). Only 4.7% males and 8.6% females were treated with AM.ConclusionsHip fractures, especially femoral neck fractures, accounted for the majority of osteoporotic fractures in a tertiary public hospital in Northeast China. Common comorbidities in these fracture patients were hyperlipemia and hypertension. There was a very low rate of AM use among these patients. |
| format | Article |
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| institution | Kabale University |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Endocrinology |
| spelling | doaj-art-5f2d51adcccc4e279d8fb59ae024dfcf2025-01-07T05:23:56ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-01-011510.3389/fendo.2024.15202291520229A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast ChinaQi Meng0Qi Meng1Xinwei Wang2Yuzhong Gao3William D. Leslie4Lisa M. Lix5Xianbao Shi6Bo Kan7Shuman Yang8Shuman Yang9Department of Endocrinology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, ChinaDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, ChinaDepartment of Internal Medicine, University of Manitoba, Winnipeg, MB, CanadaDepartment of Community Health Sciences, University of Manitoba, Winnipeg, MB, CanadaDepartment of Pharmacy, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, ChinaDepartment of Clinical Laboratory, The Second Hospital of Jilin University, Changchun, Jilin, ChinaDepartment of Endocrinology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, ChinaContextThere are limited real-world data evidence assessing the clinical characteristics of hospitalized osteoporotic fractures in China.ObjectiveTo investigate the clinical characteristics of hospitalized major osteoporotic fractures in Northeast China.MethodsWe identified hospitalized fracture patients aged 50 and over from the First Affiliated Hospital of Jinzhou Medical University between January 1, 2018, and December 31, 2022. Major osteoporotic fractures including hip, vertebral, forearm and wrist, and humerus were diagnosed based on x-ray reports extracted from the electronic medical records (EMR). The cause of fracture, comorbidities, surgical methods, and anti-osteoporotic medications (AM) use were extracted from EMR.ResultsThe study population included 1823 fracture patients, 510 males and 1313 females. Over half of fracture patients were aged over 70 years. Hip fractures accounted for 68.4% of all fractures in males and 57.9% in females. For those with hip fractures, the most common sites were the femoral neck (62.9%) and intertrochanteric (35.3%). Most fractures were due to falls (81.0% in males and 80.2% in females). The two most common comorbidities for males and females were hyperlipemia (45.9% vs. 47.1%) and hypertension (38.2% vs. 41.6%). Only 4.7% males and 8.6% females were treated with AM.ConclusionsHip fractures, especially femoral neck fractures, accounted for the majority of osteoporotic fractures in a tertiary public hospital in Northeast China. Common comorbidities in these fracture patients were hyperlipemia and hypertension. There was a very low rate of AM use among these patients.https://www.frontiersin.org/articles/10.3389/fendo.2024.1520229/fullosteoporotic fracturesepidemiologyreal-world analysiscase seriesaged people |
| spellingShingle | Qi Meng Qi Meng Xinwei Wang Yuzhong Gao William D. Leslie Lisa M. Lix Xianbao Shi Bo Kan Shuman Yang Shuman Yang A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China Frontiers in Endocrinology osteoporotic fractures epidemiology real-world analysis case series aged people |
| title | A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China |
| title_full | A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China |
| title_fullStr | A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China |
| title_full_unstemmed | A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China |
| title_short | A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China |
| title_sort | real world analysis of 1 823 hospitalized osteoporotic fractures in northeast china |
| topic | osteoporotic fractures epidemiology real-world analysis case series aged people |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1520229/full |
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