Exploring the causal impact of body mass index on metabolic biomarkers and cholelithiasis risk: a Mendelian randomization analysis

Exploring the causal impact of body mass index on metabolic biomarkers and cholelithiasis risk: a Mendelian randomization analysis

Abstract Obesity is a well-established risk factor for various diseases, but the mechanisms through which it influences disease development remain unclear. Using Mendelian randomization (MR) analysis, we examined the causal relationship between BMI, 249 metabolic traits, and cholelithiasis. BMI data...

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Bibliographic Details
Main Authors: Feng Zhao, Yanjiang Yang, Wenwen Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Body Mass Index
Metabolic Biomarkers
Cholelithiasis
Mendelian Randomization
Online Access:https://doi.org/10.1038/s41598-024-83217-6
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