Associations of severe climate conditions and race/ethnic-specific ischemic heart disease mortality among middle-aged adults in the United States

Ischemic heart disease (IHD) is the leading cause of death worldwide. In the United States, IHD deaths affect millions of adults, with substantial age and race/ethnic-specific variability. In recent years, emphasis has been placed on reducing the rate of IHD events among middle-aged adults. Non-Hisp...

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Bibliographic Details
Main Authors: Haris Majeed, Hamnah Majeed, Emmanuel Moss, Renzo Cecere, Evan G Wong
Format: Article
Language:English
Published: IOP Publishing 2024-01-01
Series:Environmental Research: Health
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Online Access:https://doi.org/10.1088/2752-5309/ad9ac3
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Summary:Ischemic heart disease (IHD) is the leading cause of death worldwide. In the United States, IHD deaths affect millions of adults, with substantial age and race/ethnic-specific variability. In recent years, emphasis has been placed on reducing the rate of IHD events among middle-aged adults. Non-Hispanic (NH) Black populations are known to have greater IHD mortality rates compared to other races/ethnicities. Researchers have established several biological, clinical, and socioeconomic IHD risk factors, but severe climate conditions have not been explored by race/ethnicity among middle-aged adults. Using generalized linear models, this study documents associations between the Palmer Drought Severity Index and race/ethnic-specific IHD mortality rates from January 1999 to December 2020 among middle-aged adults across four census regions of the United States. When controlling for covariates, we found that during months of severe droughts (in comparison to neutral phases) IHD mortality rates had an increased risk for NH Whites (RR 1.017, P = 0.017) and NH Blacks (RR 1.029, P = 0.015). Furthermore, we found that surface air temperature is a modifier, where during warm periods (⩾20 °C) throughout the United States, severe drought months exacerbated the risk of IHD mortality rates among NH White (RR 1.024, P = 0.007) and NH Blacks (RR 1.033, P = 0.039). Further studies are needed to understand the mechanism between severe climate conditions and race/ethnic-specific IHD events.
ISSN:2752-5309