A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression

A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression

Abstract Background Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus focused on cellul...

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Main Authors: Reina Sonehara, Tomoko Nakamura, Takehiko Takeda, Satoshi Kaseki, Tomomi Seki, Hideaki Tanaka, Atsushi Yabuki, Natsuki Miyake, Ayako Muraoka, Satoko Osuka, Akira Iwase, Hiroaki Kajiyama
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Reproductive Biology and Endocrinology
Subjects:
Endometriosis
Cellular senescence
SASP
IL-6
Senotherapy
Azithromycin
Online Access:https://doi.org/10.1186/s12958-025-01381-4
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