‎Shannon Entropy Analysis of Serum C-Terminal Agrin Fragment as a Biomarker for Kidney Function‎: ‎Reference‎ ‎Ranges‎, ‎Healing Sequences and Insights

This article focuses on evaluating the success or failure of kidney transplantation using Shannon entropy‎, ‎fuzzy sets‎, ‎and Scaf‎. ‎The data for Scaf references used in this study for both healthy individuals and kidney transplant recipients have been collected from the relevant literature‎. ‎For...

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Bibliographic Details
Main Author: Mehmet Sengonul
Format: Article
Language:English
Published: Islamic Azad University, Bandar Abbas Branch 2024-05-01
Series:Transactions on Fuzzy Sets and Systems
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Online Access:https://sanad.iau.ir/journal/tfss/Article/977396
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Summary:This article focuses on evaluating the success or failure of kidney transplantation using Shannon entropy‎, ‎fuzzy sets‎, ‎and Scaf‎. ‎The data for Scaf references used in this study for both healthy individuals and kidney transplant recipients have been collected from the relevant literature‎. ‎For both groups‎, ‎Scaf's Shannon entropy values have been calculated using an appropriate probability density function and formulation‎, ‎and sequences have been generated for CAF and Scr biomarkers from entropy values‎, ‎with findings interpreted‎. ‎These sequences are called healing sequences‎. ‎A case study demonstrating whether the transplant procedure was successful or unsuccessful was presented using sequences that we refer to as healing sequences‎. ‎In this context‎, ‎the utilization of mathematical tools such as fuzzy sets‎, ‎Shannon entropy‎, ‎and reference intervals becomes evident‎. ‎These tools provide a systematic and quantitative approach to assessing the outcomes of kidney transplantation‎. ‎By leveraging the principles of Shannon entropy‎, ‎we gain insights into the degree of unpredictability and fuzziness associated with biomarker values‎, ‎which can be indicative of the transplant's success‎. ‎Furthermore‎, ‎the concept of healing sequences provides a valuable framework for tracking the progression of patients post-transplantation‎. ‎By monitoring changes in CAF and Scr biomarkers over time‎, ‎healthcare professionals can make informed decisions and interventions to ensure the well-being of kidney transplant recipients‎.
ISSN:2821-0131