The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers
<b>Aim:</b> The purpose of this study was to prepare bivalent inactive Ornithobacterium rhinotracheale [O. rhinotarcheale) bacterin vaccines, to measure the levels of antibodies against antigens in blood sera and to determine the efficacies of different O. rhinotracheale vaccines in broi...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=574 |
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| Summary: | <b>Aim:</b> The purpose of this study was to prepare bivalent inactive Ornithobacterium rhinotracheale [O. rhinotarcheale) bacterin vaccines, to measure the levels of antibodies against antigens in blood sera and to determine the efficacies of different O. rhinotracheale vaccines in broilers.<p>
<b>Materials and Methods:</b> The bivalent inactivated O. rhinotracheale bacterin vaccines were prepared from O. rhinotracheale serotype A and B strains using aluminium hydroxide (Al[OH]<sub>3</sub>), mineral oil (MO), aluminium hydroxide + ginseng (Al[OH]<sub>3</sub> + G) and mineral oil + ginseng (MO + G). After the sterility and the safety tests, laboratory efficiencies of vaccines (challange/protection and serological potency) were controlled on the broilers (vaccinated at first day with a dose of 0.1 mL).<p>
<b>Results:</b> According to the challenge results, all the vaccines were found to be effective as 100% for broilers. The vaccine containing mineral oil and ginseng (MO + G) as adjuvant induced significantly greater humoral immune response to the antigens than others.<p>
<b>Conclusion:</b> The study showed that vaccination of broilers chicken at the first day age may effectively protect against O. rhinotracheale infections. |
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| ISSN: | 1309-6958 2146-1953 |