Insulin resistance, cognition, and functional brain network topology in older adults with obesity

Abstract Cross-sectional data from a sample of older adults with obesity was used to determine how peripheral insulin resistance (PIR) and neuronal insulin signaling abnormalities (NISAs) relate to executive function and functional brain network topology. Older adults (n = 71) with obesity but witho...

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Bibliographic Details
Main Authors: Clayton C. McIntyre, Robert G. Lyday, Yixin Su, Barbara Nicklas, Sean L. Simpson, Gagan Deep, Shannon L. Macauley, Christina E. Hugenschmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-06038-1
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