Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources
Polyunsaturated fatty acids (PUFAs) are vital dietary elements that play a significant role in human nutrition. They are highly regarded for their positive contributions to overall health and well-being. Beyond the fact that they provide a substantial supply of energy to the body (a role that satura...
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2024-12-01
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| author | Magdalena Mititelu Dumitru Lupuliasa Sorinel Marius Neacșu Gabriel Olteanu Ștefan Sebastian Busnatu Andreea Mihai Violeta Popovici Nicoleta Măru Steluța Constanța Boroghină Sebastian Mihai Corina-Bianca Ioniță-Mîndrican Alexandru Scafa-Udriște |
| author_facet | Magdalena Mititelu Dumitru Lupuliasa Sorinel Marius Neacșu Gabriel Olteanu Ștefan Sebastian Busnatu Andreea Mihai Violeta Popovici Nicoleta Măru Steluța Constanța Boroghină Sebastian Mihai Corina-Bianca Ioniță-Mîndrican Alexandru Scafa-Udriște |
| author_sort | Magdalena Mititelu |
| collection | DOAJ |
| description | Polyunsaturated fatty acids (PUFAs) are vital dietary elements that play a significant role in human nutrition. They are highly regarded for their positive contributions to overall health and well-being. Beyond the fact that they provide a substantial supply of energy to the body (a role that saturated fats can also perform), these unsaturated fatty acids and, especially, the essential ones are involved in cell membrane structure, blood pressure regulation, and coagulation; participate in the proper functioning of the immune system and assimilation of fat-soluble vitamins; influence the synthesis of pro- and anti-inflammatory substances; and protect the cardiovascular system. Modern diets like the Western diet and the American diet are rich in saturated fats found especially in fast food products, sweets, and processed foods, a fact that has led to an increase in the prevalence of metabolic diseases worldwide (obesity, type II diabetes, gout, cardiovascular disease). Nutritionists have drawn attention to the moderate consumption of saturated fats and the need to increase the intake of unsaturated fats to the detriment of saturated ones. This paper examines the biochemical roles of polyunsaturated fats, particularly essential fatty acids, and contrasts their benefits with the detrimental effects of saturated fat overconsumption. Furthermore, it highlights the necessity for dietary shifts towards increased PUFA intake to mitigate the global burden of diet-related health issues. The co-occurrence of PUFAs and polyphenols in plant-based foods highlights the sophistication of nature’s design. These bioactive compounds are not randomly distributed but are present in foods humans have consumed together historically. From traditional diets like the Mediterranean, which pairs olive oil (PUFAs and polyphenols) with vegetables and legumes, to Asian cuisines combining sesame seeds with turmeric, cultural practices have long harnessed this natural synergy. |
| format | Article |
| id | doaj-art-5dc7fe251aa74e3682112104eb76be88 |
| institution | Kabale University |
| issn | 2304-8158 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Foods |
| spelling | doaj-art-5dc7fe251aa74e3682112104eb76be882025-01-10T13:17:37ZengMDPI AGFoods2304-81582024-12-011414610.3390/foods14010046Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food SourcesMagdalena Mititelu0Dumitru Lupuliasa1Sorinel Marius Neacșu2Gabriel Olteanu3Ștefan Sebastian Busnatu4Andreea Mihai5Violeta Popovici6Nicoleta Măru7Steluța Constanța Boroghină8Sebastian Mihai9Corina-Bianca Ioniță-Mîndrican10Alexandru Scafa-Udriște11Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956 Bucharest, RomaniaDepartment of Pharmaceutical Technology and Bio-Pharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020945 Bucharest, RomaniaDepartment of Pharmaceutical Technology and Bio-Pharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020945 Bucharest, RomaniaDepartment of Clinical Laboratory and Food Safety, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956 Bucharest, RomaniaDepartment of Cardio-Thoracic Pathology, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Pulmonology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania“Costin C. Kiriţescu” National Institute of Economic Research—Center for Mountain Economics (INCE-CEMONT) of Romanian Academy, 725700 Vatra-Dornei, RomaniaDepartment of Anatomy, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, 020945 Bucharest, RomaniaDepartment of Complementary Sciences, History of Medicine and Medical Culture, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Therapeutic Chemistry, Faculty of Pharmacy, “Ovidius“ University of Constanta, 6 Căpitan Aviator Al Șerbănescu Street, 900470 Constanta, RomaniaDepartment of Toxicology, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020945 Bucharest, RomaniaDepartment of Cardio-Thoracic Pathology, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaPolyunsaturated fatty acids (PUFAs) are vital dietary elements that play a significant role in human nutrition. They are highly regarded for their positive contributions to overall health and well-being. Beyond the fact that they provide a substantial supply of energy to the body (a role that saturated fats can also perform), these unsaturated fatty acids and, especially, the essential ones are involved in cell membrane structure, blood pressure regulation, and coagulation; participate in the proper functioning of the immune system and assimilation of fat-soluble vitamins; influence the synthesis of pro- and anti-inflammatory substances; and protect the cardiovascular system. Modern diets like the Western diet and the American diet are rich in saturated fats found especially in fast food products, sweets, and processed foods, a fact that has led to an increase in the prevalence of metabolic diseases worldwide (obesity, type II diabetes, gout, cardiovascular disease). Nutritionists have drawn attention to the moderate consumption of saturated fats and the need to increase the intake of unsaturated fats to the detriment of saturated ones. This paper examines the biochemical roles of polyunsaturated fats, particularly essential fatty acids, and contrasts their benefits with the detrimental effects of saturated fat overconsumption. Furthermore, it highlights the necessity for dietary shifts towards increased PUFA intake to mitigate the global burden of diet-related health issues. The co-occurrence of PUFAs and polyphenols in plant-based foods highlights the sophistication of nature’s design. These bioactive compounds are not randomly distributed but are present in foods humans have consumed together historically. From traditional diets like the Mediterranean, which pairs olive oil (PUFAs and polyphenols) with vegetables and legumes, to Asian cuisines combining sesame seeds with turmeric, cultural practices have long harnessed this natural synergy.https://www.mdpi.com/2304-8158/14/1/46monounsaturated fatty acidspolyunsaturated fatty acidssaturated fatsmetabolic syndromeessential fatty acidsmarine lipids |
| spellingShingle | Magdalena Mititelu Dumitru Lupuliasa Sorinel Marius Neacșu Gabriel Olteanu Ștefan Sebastian Busnatu Andreea Mihai Violeta Popovici Nicoleta Măru Steluța Constanța Boroghină Sebastian Mihai Corina-Bianca Ioniță-Mîndrican Alexandru Scafa-Udriște Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources Foods monounsaturated fatty acids polyunsaturated fatty acids saturated fats metabolic syndrome essential fatty acids marine lipids |
| title | Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources |
| title_full | Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources |
| title_fullStr | Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources |
| title_full_unstemmed | Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources |
| title_short | Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources |
| title_sort | polyunsaturated fatty acids and human health a key to modern nutritional balance in association with polyphenolic compounds from food sources |
| topic | monounsaturated fatty acids polyunsaturated fatty acids saturated fats metabolic syndrome essential fatty acids marine lipids |
| url | https://www.mdpi.com/2304-8158/14/1/46 |
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