Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration

Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration

Abstract Background Thyroid hormone (T3) has an inhibitory effect on tissue/organ regeneration. It is still elusive how T3 regulates this process. It is well established that the developmental effects of T3 are primarily mediated through transcriptional regulation by thyroid hormone receptors (TRs)....

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Bibliographic Details
Main Authors: Shouhong Wang, Liezhen Fu, Bin Wang, Yanmei Cai, Jianping Jiang, Yun-Bo Shi
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Genomics
Subjects:
Thyroid hormone
TR knockout
Regeneration
Tail
Gene regulation
Xenopus tropicalis
Online Access:https://doi.org/10.1186/s12864-024-11175-4
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