Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet
Forsythia suspensa, belonging to the deciduous shrubs of the Luteaceae family, a traditional Chinese medicine, has effects of alleviating swelling, clearing heat, detoxification and promoting blood circulation. The leaves of F. suspensa contain multiple chemical components and have a long history of...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2024-03-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2022.9250055 |
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| author | Lanlan Gui Shaokang Wang Jing Wang Wang Liao Zitong Chen Da Pan Hui Xia Guiju Sun Su Tian |
| author_facet | Lanlan Gui Shaokang Wang Jing Wang Wang Liao Zitong Chen Da Pan Hui Xia Guiju Sun Su Tian |
| author_sort | Lanlan Gui |
| collection | DOAJ |
| description | Forsythia suspensa, belonging to the deciduous shrubs of the Luteaceae family, a traditional Chinese medicine, has effects of alleviating swelling, clearing heat, detoxification and promoting blood circulation. The leaves of F. suspensa contain multiple chemical components and have a long history of use in folk medicines and health foods. The purpose of this study was to explore the effects of forsythin extract from F. suspensa leaves on intestinal microbiota and short-chain fatty acid (SCFA) content in rats with obesity induced by a high-fat diet. Forsythin extract in F. suspensa leaves increased the abundance of the intestinal microbiota, ameliorated intestinal microbiota disorders and inhibited the increase in total SCFA content in the intestinal tract in rats with obesity induced by a high-fat diet. These results suggested that forsythin extract in F. suspensa leaves may slow the development of obesity induced by a high-fat diet; thus, its active components and efficacy are worthy of further study. |
| format | Article |
| id | doaj-art-5d8570e972f34938a90effb1e7e7cfa5 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-5d8570e972f34938a90effb1e7e7cfa52024-12-29T16:00:05ZengTsinghua University PressFood Science and Human Wellness2213-45302024-03-0113265966710.26599/FSHW.2022.9250055Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat dietLanlan Gui0Shaokang Wang1Jing Wang2Wang Liao3Zitong Chen4Da Pan5Hui Xia6Guiju Sun7Su Tian8Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaNanjing Municipal Center for Disease Control and Prevention, Nanjing 210003, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaNanjing Municipal Center for Disease Control and Prevention, Nanjing 210003, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Shijiazhuang 050017, ChinaForsythia suspensa, belonging to the deciduous shrubs of the Luteaceae family, a traditional Chinese medicine, has effects of alleviating swelling, clearing heat, detoxification and promoting blood circulation. The leaves of F. suspensa contain multiple chemical components and have a long history of use in folk medicines and health foods. The purpose of this study was to explore the effects of forsythin extract from F. suspensa leaves on intestinal microbiota and short-chain fatty acid (SCFA) content in rats with obesity induced by a high-fat diet. Forsythin extract in F. suspensa leaves increased the abundance of the intestinal microbiota, ameliorated intestinal microbiota disorders and inhibited the increase in total SCFA content in the intestinal tract in rats with obesity induced by a high-fat diet. These results suggested that forsythin extract in F. suspensa leaves may slow the development of obesity induced by a high-fat diet; thus, its active components and efficacy are worthy of further study.https://www.sciopen.com/article/10.26599/FSHW.2022.9250055forsythinhigh-fat dietintestinal microbiotashort-chain fatty acid (scfa) |
| spellingShingle | Lanlan Gui Shaokang Wang Jing Wang Wang Liao Zitong Chen Da Pan Hui Xia Guiju Sun Su Tian Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet Food Science and Human Wellness forsythin high-fat diet intestinal microbiota short-chain fatty acid (scfa) |
| title | Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet |
| title_full | Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet |
| title_fullStr | Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet |
| title_full_unstemmed | Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet |
| title_short | Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet |
| title_sort | effects of forsythin extract in forsythia leaves on intestinal microbiota and short chain fatty acids in rats fed a high fat diet |
| topic | forsythin high-fat diet intestinal microbiota short-chain fatty acid (scfa) |
| url | https://www.sciopen.com/article/10.26599/FSHW.2022.9250055 |
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