Genetic association between mitochondrial DNA copy number and glioma risk: insights from causality

Genetic association between mitochondrial DNA copy number and glioma risk: insights from causality

Abstract Background The genetic causal association between the mitochondrial DNA copy number (mtDNA-CN) and the development of glioma and glioblastoma (GBM) remains unclear. Methods The summary-level datasets for mtDNA-CN were obtained from participants in the UK Biobank and the Cohorts for Heart an...

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Bibliographic Details
Main Authors: Qiang He, Wenjing Wang, Dingkang Xu, Yang Xiong, Chuanyuan Tao, Lu Ma, Junpeng Ma, Songping Zheng, Chao You, Xin Zan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Glioma
Glioblastoma
Mitochondrial DNA copy number
Causal association
Online Access:https://doi.org/10.1186/s12885-024-13212-7
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https://doi.org/10.1186/s12885-024-13212-7

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