Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas

Background/Objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Opt...

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Main Authors: Maria Erasti, Martina D’Onghia, Anastasia Batsikosta, Mariano Suppa, Linda Tognetti, Simone Cappilli, Ketty Peris, Francesca La Marca, Jean Luc Perrot, Giovanni Rubegni, Pietro Rubegni, Elisa Cinotti
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Language:English
Published: MDPI AG 2024-11-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/14/23/2671
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author Maria Erasti
Martina D’Onghia
Anastasia Batsikosta
Mariano Suppa
Linda Tognetti
Simone Cappilli
Ketty Peris
Francesca La Marca
Jean Luc Perrot
Giovanni Rubegni
Pietro Rubegni
Elisa Cinotti
author_facet Maria Erasti
Martina D’Onghia
Anastasia Batsikosta
Mariano Suppa
Linda Tognetti
Simone Cappilli
Ketty Peris
Francesca La Marca
Jean Luc Perrot
Giovanni Rubegni
Pietro Rubegni
Elisa Cinotti
author_sort Maria Erasti
collection DOAJ
description Background/Objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Optical Coherence Tomography (LC-OCT), Reflectance Confocal Microscopy (RCM), and Ultra-High-Frequency Ultrasound (UHFUS), in their diagnosis. Methods: In total, seven cases of hidrocystomas were collected from the Dermatologic Clinic of the University of Siena, Italy. Predefined dermoscopic, LC-OCT, RCM, and UHFUS features were retrospectively described. Results: Overall, hidrocystomas were located on the face, mainly presenting as blue/purple-bluish translucent papules (71%). Dermoscopic examination revealed a homogeneous purple-bluish color (71%), white pale halo (71%), and shiny globules at the periphery (57%). LC-OCT identified a hyporeflective cupoliform round structure in the dermis with a bright and thick contour, while UHFUS showed a round structure in the dermis filled with hypoechoic content. Conclusions: Non-invasive imaging techniques could significantly enhance the diagnostic accuracy of hidrocystomas, aid in differentiation from other lesions, and minimize unnecessary biopsies.
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spelling doaj-art-5d1cf5d737184b75b5672a9b42a20a7d2024-12-13T16:24:36ZengMDPI AGDiagnostics2075-44182024-11-011423267110.3390/diagnostics14232671Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of HidrocystomasMaria Erasti0Martina D’Onghia1Anastasia Batsikosta2Mariano Suppa3Linda Tognetti4Simone Cappilli5Ketty Peris6Francesca La Marca7Jean Luc Perrot8Giovanni Rubegni9Pietro Rubegni10Elisa Cinotti11Dermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyDermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyPathological Anatomy Section, University of Siena, 51300 Siena, ItalyDepartment of Dermatology, Hôpital Erasme, HUB, Université Libre de Bruxelles, 1070 Brussels, BelgiumDermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyDepartment of Dermatology, Sacred Heart Catholic University, 20123 Rome, ItalyDepartment of Dermatology, Sacred Heart Catholic University, 20123 Rome, ItalyDermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyDepartment of Dermatology, University Hospital of Saint-Etienne; 42270 Saint-Etienne, FranceOphthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 51300 Siena, ItalyDermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyDermatology Unit, Department of Medical, Surgical, and Neurological Sciences, University of Siena, 51300 Siena, ItalyBackground/Objectives: Hidrocystomas, eccrine and apocrine, are rare cystic lesions that form benign tumors of the sweat glands. This study aimed to describe the clinical features of hidrocystomas and evaluate the role of non-invasive imaging techniques, including dermoscopy, Line-field Confocal Optical Coherence Tomography (LC-OCT), Reflectance Confocal Microscopy (RCM), and Ultra-High-Frequency Ultrasound (UHFUS), in their diagnosis. Methods: In total, seven cases of hidrocystomas were collected from the Dermatologic Clinic of the University of Siena, Italy. Predefined dermoscopic, LC-OCT, RCM, and UHFUS features were retrospectively described. Results: Overall, hidrocystomas were located on the face, mainly presenting as blue/purple-bluish translucent papules (71%). Dermoscopic examination revealed a homogeneous purple-bluish color (71%), white pale halo (71%), and shiny globules at the periphery (57%). LC-OCT identified a hyporeflective cupoliform round structure in the dermis with a bright and thick contour, while UHFUS showed a round structure in the dermis filled with hypoechoic content. Conclusions: Non-invasive imaging techniques could significantly enhance the diagnostic accuracy of hidrocystomas, aid in differentiation from other lesions, and minimize unnecessary biopsies.https://www.mdpi.com/2075-4418/14/23/2671hidrocystomasdermoscopyLC-OCToptical coherence tomographyRCMUHFUS
spellingShingle Maria Erasti
Martina D’Onghia
Anastasia Batsikosta
Mariano Suppa
Linda Tognetti
Simone Cappilli
Ketty Peris
Francesca La Marca
Jean Luc Perrot
Giovanni Rubegni
Pietro Rubegni
Elisa Cinotti
Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
Diagnostics
hidrocystomas
dermoscopy
LC-OCT
optical coherence tomography
RCM
UHFUS
title Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
title_full Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
title_fullStr Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
title_full_unstemmed Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
title_short Dermoscopy, Line-Field Confocal Optical Coherence Tomography, Reflectance Confocal Microscopy, and Ultra-High-Frequency Ultrasound: Clues for the Diagnosis of Hidrocystomas
title_sort dermoscopy line field confocal optical coherence tomography reflectance confocal microscopy and ultra high frequency ultrasound clues for the diagnosis of hidrocystomas
topic hidrocystomas
dermoscopy
LC-OCT
optical coherence tomography
RCM
UHFUS
url https://www.mdpi.com/2075-4418/14/23/2671
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