Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats

Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats

<b>Background/Objectives:</b> Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease characterized by a protracted course, high rates of morbidity, and disability yet lacks effective therapeutic modalities. Levamisole (LVM), an immunomodulatory drug, has been clinically repor...

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Main Authors: Mu Guo, Xiangbin Yu, Zesheng Yang, Hanlu Zheng, Jiahui Zhang, Junxiang Wang, Yiqi Liao, Weirui Huang, Zhaolong Lin, Yingxue Yan, Nengfu Qiu, Jianmin Chen, Yue Yu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
levamisole
rheumatoid arthritis
adjuvant-induced arthritis
PI3K/Akt signaling pathway
Sprague–Dawley rat
Online Access:https://www.mdpi.com/1424-8247/17/11/1504
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