Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer

Exon 1 methylation status of CDH13 is associated with decreased overall survival and distant metastasis in patients with postoperative colorectal cancer

Abstract Background Cadherin 13 (CDH13) is a member of the cadherin superfamily that exerts tumor-suppressive effects on cancers derived from epithelial cells. Although hypermethylation of CDH13 promoter has been reported in various cancers, its prognostic value for colorectal cancer (CRC) is still...

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Bibliographic Details
Main Authors: PengCheng Xiang, PengJu Li, Xiaoqi Yuan, Xiuhao Zhao, Zitian Xiao, Bingguan Chen, Kenwen Liu, Evelyne Bischof, Junyi Han
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
Colorectal cancer (CRC)
CDH13 gene
Methylation
CpG site
Online Access:https://doi.org/10.1007/s12672-024-01604-x
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