The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke

The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke

IntroductionIschemic strokes contribute significantly to cardiovascular-related deaths in the U.S., with current interventions limited to thrombolytic agents. However, these agents present challenges such as a limited therapeutic window, incomplete reperfusion rates, risk of transformation, reperfus...

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Bibliographic Details
Main Authors: Katherine Hernandez, Nathan Jones, Sterling B. Ortega
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
Subjects:
PNU-120596
CD4 T-cells
stroke
TMCAO
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1525975/full
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