Biological importance and synthesis of 1,2,3-triazole derivatives: a review

1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential molecules are under clinical investigation. Theref...

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Main Authors: Mira J. Vaishnani, Sabera Bijani, Mohamed Rahamathulla, Lalji Baldaniya, Vicky Jain, Kamal Y. Thajudeen, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Ismail Pasha
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Green Chemistry Letters and Reviews
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Online Access:https://www.tandfonline.com/doi/10.1080/17518253.2024.2307989
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author Mira J. Vaishnani
Sabera Bijani
Mohamed Rahamathulla
Lalji Baldaniya
Vicky Jain
Kamal Y. Thajudeen
Mohammed Muqtader Ahmed
Syeda Ayesha Farhana
Ismail Pasha
author_facet Mira J. Vaishnani
Sabera Bijani
Mohamed Rahamathulla
Lalji Baldaniya
Vicky Jain
Kamal Y. Thajudeen
Mohammed Muqtader Ahmed
Syeda Ayesha Farhana
Ismail Pasha
author_sort Mira J. Vaishnani
collection DOAJ
description 1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential molecules are under clinical investigation. Therefore, it is fairly reasonable to anticipate that there will be an increase in demand for new triazole-containing drugs in the coming future. Because of its broad pharmacological applications, it has recently attracted the attention of scientists worldwide. This review provides a concise summary of the synthetic techniques for triazole compounds from various strategies and their medical importance as a lead structure for the enhancement of therapeutic molecules.
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series Green Chemistry Letters and Reviews
spelling doaj-art-5c9767d1525047599b0ab90e28a50f552024-12-06T01:41:31ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922024-12-0117110.1080/17518253.2024.2307989Biological importance and synthesis of 1,2,3-triazole derivatives: a reviewMira J. Vaishnani0Sabera Bijani1Mohamed Rahamathulla2Lalji Baldaniya3Vicky Jain4Kamal Y. Thajudeen5Mohammed Muqtader Ahmed6Syeda Ayesha Farhana7Ismail Pasha8Department of Chemistry, Marwadi University, Rajkot, IndiaDepartment of Chemistry, Marwadi University, Rajkot, IndiaDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi ArabiaDepartment of Pharmaceutical Sciences, Marwadi University, Rajkot, IndiaDepartment of Chemistry, Marwadi University, Rajkot, IndiaDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, Abha, Saudi ArabiaDepartment of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi ArabiaDepartment of Pharmaceutics, Unaizah College of Pharmacy, Qassim University, Unaizah, Saudi ArabiaDepartment of Pharmacology, Orotta College of Medicine and Health Science. Asmara, Eritrea1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential molecules are under clinical investigation. Therefore, it is fairly reasonable to anticipate that there will be an increase in demand for new triazole-containing drugs in the coming future. Because of its broad pharmacological applications, it has recently attracted the attention of scientists worldwide. This review provides a concise summary of the synthetic techniques for triazole compounds from various strategies and their medical importance as a lead structure for the enhancement of therapeutic molecules.https://www.tandfonline.com/doi/10.1080/17518253.2024.23079891,2,3triazoleclick chemistryazide-alkynes cycloadditionbiological importanceHuisgen azide–alkyne cycloaddition
spellingShingle Mira J. Vaishnani
Sabera Bijani
Mohamed Rahamathulla
Lalji Baldaniya
Vicky Jain
Kamal Y. Thajudeen
Mohammed Muqtader Ahmed
Syeda Ayesha Farhana
Ismail Pasha
Biological importance and synthesis of 1,2,3-triazole derivatives: a review
Green Chemistry Letters and Reviews
1,2,3triazole
click chemistry
azide-alkynes cycloaddition
biological importance
Huisgen azide–alkyne cycloaddition
title Biological importance and synthesis of 1,2,3-triazole derivatives: a review
title_full Biological importance and synthesis of 1,2,3-triazole derivatives: a review
title_fullStr Biological importance and synthesis of 1,2,3-triazole derivatives: a review
title_full_unstemmed Biological importance and synthesis of 1,2,3-triazole derivatives: a review
title_short Biological importance and synthesis of 1,2,3-triazole derivatives: a review
title_sort biological importance and synthesis of 1 2 3 triazole derivatives a review
topic 1,2,3triazole
click chemistry
azide-alkynes cycloaddition
biological importance
Huisgen azide–alkyne cycloaddition
url https://www.tandfonline.com/doi/10.1080/17518253.2024.2307989
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