Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from Loxosceles spiders

Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from Loxosceles spiders

The Phospholipase D (PLD) toxin family, a major component of the Loxosceles spider venom, is a valuable biotechnological tool for developing antivenom treatment and diagnostic assays to overcome and prevent loxoscelism. However, there is limited knowledge about the antigenic structure of the PLD fam...

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Bibliographic Details
Main Authors: Alejandro Catalán, Carolina García, Valentina Sambra, Nicole Cadena, José Rojas, Tomás Arán-Sekul, Juan San Francisco, Valeria Vásquez-Saez, Christian Muñoz, Abel Vásquez, Jorge E. Araya
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Toxicon: X
Subjects:
Antigenic structure
Loxosceles species
Epitope variation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171025000098
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