Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy

Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy

Abstract Background Treponemal diseases are a significant global health risk, presenting challenges to public health and severe consequences to individuals if left untreated. Despite numerous genomic studies on Treponema pallidum and the known possible biases introduced by the choice of the referenc...

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Main Authors: Marta Pla-Díaz, Gülfirde Akgül, Martyna Molak, Louis du Plessis, Hanna Panagiotopoulou, Karolina Doan, Wiesław Bogdanowicz, Paweł Dąbrowski, Maciej Oziembłowski, Barbara Kwiatkowska, Jacek Szczurowski, Joanna Grzelak, Natasha Arora, Kerttu Majander, Fernando González-Candelas, Verena J. Schuenemann
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Biology
Subjects:
Treponematoses
Mapping strategy
Reference genome selection
Bacterial recombination
Natural selection
Timescale estimation
Online Access:https://doi.org/10.1186/s12915-024-02108-4
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