Phosphorylated pullulan as a local drug delivery matrix for cationic antibacterial chemicals to prevent oral biofilm

Phosphorylated pullulan as a local drug delivery matrix for cationic antibacterial chemicals to prevent oral biofilm

Abstract Background Preventing oral infections, such as oral caries and periodontal disease, helps reduce the risks of various systemic diseases. In this study, the polysaccharide pullulan produced by the black yeast Aureobasidium pullulans was modified in combination with the cationic surfactant ce...

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Main Authors: Naoko Namba-Koide, Yasuhiro Yoshida, Noriyuki Nagaoka, Takumi Okihara, Yusuke Kawata, Masahiro Ito, Takashi Ito, Kazu Takeuchi-Hatanaka, Yuki Shinoda-Ito, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Oral Health
Subjects:
Phosphorylated Pullulan
Local drug delivery system
Cationic antimicrobial agents
Cetylpyridinium chloride
Oral biofilm
Online Access:https://doi.org/10.1186/s12903-025-06666-z
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https://doi.org/10.1186/s12903-025-06666-z

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