Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice

Circadian rhythm perturbation causes IBS-like characteristics and altered fecal metabolome in mice

Abstract Background Circadian rhythm disturbance is associated with functional gastrointestinal disorders such as irritable bowel syndrome (IBS). This study aimed to explore the effects of dysregulated circadian rhythm on visceral sensitivity, colonic permeability, gut microbial composition, and met...

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Main Authors: Gaichao Hong, Yajuan Zhao, Jieru Zhou, Lilin Hu, Gangping Li, Yu Jin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Microbiology
Subjects:
Circadian rhythm disturbance
Phase shift
IBS
Gut microbiota
Metabolism
Online Access:https://doi.org/10.1186/s12866-025-04009-0
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https://doi.org/10.1186/s12866-025-04009-0

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