TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry
Aims: To compare the lung functions of TOPD phenotype patients and COPD patients other than TOPD phenotype. Settings and design: Retro-prospective cohort study. Introduction: Globally, tuberculosis (TB) has emerged as a risk factor for the development of chronic obstructive pulmonary disease (COPD)...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-06-01
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| Series: | The Journal of Association of Chest Physicians |
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| Online Access: | https://journals.lww.com/10.4103/jacp.jacp_57_23 |
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| author | Bishal Debbarma Anand Srivastava Sapna Dixit Rajiv Garg S.K Verma RAS Kushwaha Santosh Kumar Ajay Kumar Verma Darshan Kumar Bajaj Ankit Kumar Jyoti Bajpai Surya Kant |
| author_facet | Bishal Debbarma Anand Srivastava Sapna Dixit Rajiv Garg S.K Verma RAS Kushwaha Santosh Kumar Ajay Kumar Verma Darshan Kumar Bajaj Ankit Kumar Jyoti Bajpai Surya Kant |
| author_sort | Bishal Debbarma |
| collection | DOAJ |
| description | Aims: To compare the lung functions of TOPD phenotype patients and COPD patients other than TOPD phenotype. Settings and design: Retro-prospective cohort study. Introduction: Globally, tuberculosis (TB) has emerged as a risk factor for the development of chronic obstructive pulmonary disease (COPD) and is one of the leading causes of mortality and morbidity. This entity has been titled as TOPD phenotype (tuberculosis-associated obstructive pulmonary disease), and it has been mentioned in various literatures in the past by various authors. However, it is still a matter of debate whether pattern of chronic airflow obstruction in COPD and TOPD phenotype is different or same. Methodology: We enrolled a total of 100 patients, in that 50 of whom had obstructive airway symptoms with a history of (treated) pulmonary tuberculosis (with a microbiological or radiological evidence in the past) and 50 of whom were diagnosed with COPD without any history of tuberculosis. Both groups underwent spirometry and impulse oscillometry (IOS) tests. Results were recorded and compared. Results: The mean age of patients with TOPD was 49.51 ± 5.15, while COPD was 48.54 ± 5.94. The chance of exacerbation was higher in the TOPD group (94.0%) owing to poor lung function. The majority of TOPD patients were in GOLD II stage, while COPD patients were in GOLD I stage. Spirometry and IOS of TOPD patients revealed a significant difference as compared to COPD patients. Conclusion: We found that overall lung function was poorer in the TOPD group as compared to the COPD group. |
| format | Article |
| id | doaj-art-5c2689028259486ea593affe19a65eab |
| institution | Kabale University |
| issn | 2320-8775 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Journal of Association of Chest Physicians |
| spelling | doaj-art-5c2689028259486ea593affe19a65eab2025-01-04T10:13:10ZengWolters Kluwer Medknow PublicationsThe Journal of Association of Chest Physicians2320-87752024-06-01122829010.4103/jacp.jacp_57_23TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of SpirometryBishal DebbarmaAnand SrivastavaSapna DixitRajiv GargS.K VermaRAS KushwahaSantosh KumarAjay Kumar VermaDarshan Kumar BajajAnkit KumarJyoti BajpaiSurya KantAims: To compare the lung functions of TOPD phenotype patients and COPD patients other than TOPD phenotype. Settings and design: Retro-prospective cohort study. Introduction: Globally, tuberculosis (TB) has emerged as a risk factor for the development of chronic obstructive pulmonary disease (COPD) and is one of the leading causes of mortality and morbidity. This entity has been titled as TOPD phenotype (tuberculosis-associated obstructive pulmonary disease), and it has been mentioned in various literatures in the past by various authors. However, it is still a matter of debate whether pattern of chronic airflow obstruction in COPD and TOPD phenotype is different or same. Methodology: We enrolled a total of 100 patients, in that 50 of whom had obstructive airway symptoms with a history of (treated) pulmonary tuberculosis (with a microbiological or radiological evidence in the past) and 50 of whom were diagnosed with COPD without any history of tuberculosis. Both groups underwent spirometry and impulse oscillometry (IOS) tests. Results were recorded and compared. Results: The mean age of patients with TOPD was 49.51 ± 5.15, while COPD was 48.54 ± 5.94. The chance of exacerbation was higher in the TOPD group (94.0%) owing to poor lung function. The majority of TOPD patients were in GOLD II stage, while COPD patients were in GOLD I stage. Spirometry and IOS of TOPD patients revealed a significant difference as compared to COPD patients. Conclusion: We found that overall lung function was poorer in the TOPD group as compared to the COPD group.https://journals.lww.com/10.4103/jacp.jacp_57_23tuberculosischronic obstructive pulmonary diseasepost tuberculosis obstructive pulmonary diseasetopdspirometryimpulse oscillometryforced oscillatory techniquefot |
| spellingShingle | Bishal Debbarma Anand Srivastava Sapna Dixit Rajiv Garg S.K Verma RAS Kushwaha Santosh Kumar Ajay Kumar Verma Darshan Kumar Bajaj Ankit Kumar Jyoti Bajpai Surya Kant TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry The Journal of Association of Chest Physicians tuberculosis chronic obstructive pulmonary disease post tuberculosis obstructive pulmonary disease topd spirometry impulse oscillometry forced oscillatory technique fot |
| title | TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry |
| title_full | TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry |
| title_fullStr | TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry |
| title_full_unstemmed | TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry |
| title_short | TOPD Phenotype versus COPD: Pulmonary Function Spectrum Beyond the Limits of Spirometry |
| title_sort | topd phenotype versus copd pulmonary function spectrum beyond the limits of spirometry |
| topic | tuberculosis chronic obstructive pulmonary disease post tuberculosis obstructive pulmonary disease topd spirometry impulse oscillometry forced oscillatory technique fot |
| url | https://journals.lww.com/10.4103/jacp.jacp_57_23 |
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