A Phenylalanine Ammonia Lyase Capacitive Sensor for Phenylalanine Detection
In this paper, an easy-to-use and fast biosensor for phenylalanine quantification in patients affected by phenylketonuria is investigated. The phenylalanine concentration was indirectly estimated through the ammonia released as a by-product of an enzymatic reaction, which was then detected by exploi...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-03-01
|
| Series: | Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2504-3900/97/1/51 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | In this paper, an easy-to-use and fast biosensor for phenylalanine quantification in patients affected by phenylketonuria is investigated. The phenylalanine concentration was indirectly estimated through the ammonia released as a by-product of an enzymatic reaction, which was then detected by exploiting an yttria-stabilized zirconia layer deposited over an interdigitated capacitive sensor. The latter was manufactured by rapid-prototyping technologies. A sensor limit of detection higher than 1.25 µM was estimated, along with an accuracy better than 18.31 µM. |
|---|---|
| ISSN: | 2504-3900 |