The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?

Abstract Diverticular disease (DD) is widespread worldwide. The role of gut microbiota (GM) in DD is not entirely understood.  Here we discuss the significance of the current knowledge on GM in the different stages of DD and how crucial these acquisitions are for designing diagnostic and therapeutic...

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Main Authors: Antonio Tursi, Alfredo Papa
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-024-01426-0
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author Antonio Tursi
Alfredo Papa
author_facet Antonio Tursi
Alfredo Papa
author_sort Antonio Tursi
collection DOAJ
description Abstract Diverticular disease (DD) is widespread worldwide. The role of gut microbiota (GM) in DD is not entirely understood.  Here we discuss the significance of the current knowledge on GM in the different stages of DD and how crucial these acquisitions are for designing diagnostic and therapeutic trials in this field.
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institution Kabale University
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publishDate 2024-12-01
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series Genome Medicine
spelling doaj-art-5ba0e7f8e39042998f0e7e5a9b9e2fc62025-01-05T12:42:18ZengBMCGenome Medicine1756-994X2024-12-011611410.1186/s13073-024-01426-0The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?Antonio Tursi0Alfredo Papa1Territorial Gastroenterology Service, Barletta-Andria-Trani Local Health AgencyDepartment of Medical and Surgical Sciences, Digestive Diseases Centre (CEMAD), Policlinico Universitario “A. Gemelli” Foundation, IRCCSAbstract Diverticular disease (DD) is widespread worldwide. The role of gut microbiota (GM) in DD is not entirely understood.  Here we discuss the significance of the current knowledge on GM in the different stages of DD and how crucial these acquisitions are for designing diagnostic and therapeutic trials in this field.https://doi.org/10.1186/s13073-024-01426-0DiverticulosisSymptomatic uncomplicated diverticular diseaseAcute diverticulitisGut microbiota
spellingShingle Antonio Tursi
Alfredo Papa
The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
Genome Medicine
Diverticulosis
Symptomatic uncomplicated diverticular disease
Acute diverticulitis
Gut microbiota
title The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
title_full The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
title_fullStr The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
title_full_unstemmed The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
title_short The role of gut microbiota in the pathogenesis of diverticular disease: where are we now?
title_sort role of gut microbiota in the pathogenesis of diverticular disease where are we now
topic Diverticulosis
Symptomatic uncomplicated diverticular disease
Acute diverticulitis
Gut microbiota
url https://doi.org/10.1186/s13073-024-01426-0
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