Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review

Non-ketotic hyperglycemia-induced hemichorea-hemiballism (NKHHH) is an infrequent hyperkinetic movement disorder, also known as diabetic striatopathy or Chorea hyperglycemia basal ganglia syndrome (C-H-BG), characterized by repetitive, uncontrollable movements in the unilateral or bilateral limbs. A...

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Main Authors: Praveen K. Sharma, Abdul Majith Seeni Mohammed, Seetha Rashi, Sakthi Ganesh Subramonian
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2024-09-01
Series:Romanian Journal of Neurology
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Online Access:https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-14.pdf
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author Praveen K. Sharma
Abdul Majith Seeni Mohammed
Seetha Rashi
Sakthi Ganesh Subramonian
author_facet Praveen K. Sharma
Abdul Majith Seeni Mohammed
Seetha Rashi
Sakthi Ganesh Subramonian
author_sort Praveen K. Sharma
collection DOAJ
description Non-ketotic hyperglycemia-induced hemichorea-hemiballism (NKHHH) is an infrequent hyperkinetic movement disorder, also known as diabetic striatopathy or Chorea hyperglycemia basal ganglia syndrome (C-H-BG), characterized by repetitive, uncontrollable movements in the unilateral or bilateral limbs. An insult to the contralateral basal ganglia causes NKHHH to develop. NKHHH is caused by ischemia, followed by non-ketotic hyperglycemia and poorly controlled diabetes. NKHHH is a rare condition with a unique cause that only affects one side of the corpus striatum (caudate nucleus and putamen). Clinical events of hemichorea-hemiballism, laboratory tests (elevated blood glucose and hemoglobin A1c levels), and imaging modalities (computed tomography and magnetic resonance imaging) all contribute to diagnosing NKHHH. The objective of this case report is to represent cross-sectional imaging findings in a 55-year-old female who presented with hemichorea-hemiballism following non-ketotic hyperglycemia. In conclusion, the clinical manifestation of NKHHH and its computed tomography (CT) and magnetic resonance imaging (MRI) findings are crucial in determining the appropriate management.
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institution Kabale University
issn 1843-8148
2069-6094
language English
publishDate 2024-09-01
publisher Amaltea Medical Publishing House
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series Romanian Journal of Neurology
spelling doaj-art-5b257cd407e547d39e84dcb6c42f1cbc2024-12-11T10:43:25ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942024-09-0123331632310.37897/RJN.2024.3.14Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature reviewPraveen K. Sharma0Abdul Majith Seeni Mohammed1Seetha Rashi2Sakthi Ganesh Subramonian3Department of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, IndiaDepartment of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, IndiaDepartment of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, IndiaDepartment of Radiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, IndiaNon-ketotic hyperglycemia-induced hemichorea-hemiballism (NKHHH) is an infrequent hyperkinetic movement disorder, also known as diabetic striatopathy or Chorea hyperglycemia basal ganglia syndrome (C-H-BG), characterized by repetitive, uncontrollable movements in the unilateral or bilateral limbs. An insult to the contralateral basal ganglia causes NKHHH to develop. NKHHH is caused by ischemia, followed by non-ketotic hyperglycemia and poorly controlled diabetes. NKHHH is a rare condition with a unique cause that only affects one side of the corpus striatum (caudate nucleus and putamen). Clinical events of hemichorea-hemiballism, laboratory tests (elevated blood glucose and hemoglobin A1c levels), and imaging modalities (computed tomography and magnetic resonance imaging) all contribute to diagnosing NKHHH. The objective of this case report is to represent cross-sectional imaging findings in a 55-year-old female who presented with hemichorea-hemiballism following non-ketotic hyperglycemia. In conclusion, the clinical manifestation of NKHHH and its computed tomography (CT) and magnetic resonance imaging (MRI) findings are crucial in determining the appropriate management.https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-14.pdfhyperglycemiachoreahyperkinesiscaudate nucleuscomputed tomographymagnetic resonance imaging
spellingShingle Praveen K. Sharma
Abdul Majith Seeni Mohammed
Seetha Rashi
Sakthi Ganesh Subramonian
Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
Romanian Journal of Neurology
hyperglycemia
chorea
hyperkinesis
caudate nucleus
computed tomography
magnetic resonance imaging
title Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
title_full Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
title_fullStr Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
title_full_unstemmed Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
title_short Non-ketotic hyperglycemia-induced hemichoreahemiballism – A case presentation and literature review
title_sort non ketotic hyperglycemia induced hemichoreahemiballism a case presentation and literature review
topic hyperglycemia
chorea
hyperkinesis
caudate nucleus
computed tomography
magnetic resonance imaging
url https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-14.pdf
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AT seetharashi nonketotichyperglycemiainducedhemichoreahemiballismacasepresentationandliteraturereview
AT sakthiganeshsubramonian nonketotichyperglycemiainducedhemichoreahemiballismacasepresentationandliteraturereview