Determination of QLNC-3A6 in canine plasma by UHPLC-MS/MS and its application in pharmacokinetic studies

Multi-targeted tyrosine kinase inhibitor QLNC-3A6 Di-maleate, a structurally novel small molecule compound, has therapeutic efficacy for the treatment of canine cutaneous mast cell tumor (CMCT) caused by mutations in the c-Kit gene. Since pharmacokinetic (PK) information plays an important role in t...

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Bibliographic Details
Main Authors: Sumeng Chen, Yu Liu, Yue Wang, Zeyu Wen, Jinyan Meng, Yuxin Yang, Yang Zhang, Mei Kong, Gang Chen, Xingyuan Cao
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Veterinary Quarterly
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Online Access:https://www.tandfonline.com/doi/10.1080/01652176.2024.2407174
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