TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
TiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the abil...
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Format: | Article |
Language: | English |
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Termedia Publishing House
2021-06-01
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Series: | Gastroenterology Review |
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Online Access: | https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.html |
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author | Sara Jarmakiewicz-Czaja Aneta Sokal Jacek Tabarkiewicz Rafał Filip |
author_facet | Sara Jarmakiewicz-Czaja Aneta Sokal Jacek Tabarkiewicz Rafał Filip |
author_sort | Sara Jarmakiewicz-Czaja |
collection | DOAJ |
description | TiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the ability to accumulate in some internal organs, like spleen, liver, and kidneys, depending on its size and structure. It may have pro-inflammatory, cytotoxic, and genotoxic effects. A change in the composition of the host’s intestinal microflora is also observed after exposure to high doses of TiO2. There are some differences in TiO2 intake with food around the world, but most data indicate higher consumption of this additive by children. Due to the small amount of research and the fact that most of the analyses were carried out using animal models, it is necessary to plan future observations of long-term exposure of the TiO2 molecule. |
format | Article |
id | doaj-art-5a85848778624e98a60f557e26d77b7c |
institution | Kabale University |
issn | 1895-5770 1897-4317 |
language | English |
publishDate | 2021-06-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Gastroenterology Review |
spelling | doaj-art-5a85848778624e98a60f557e26d77b7c2025-01-10T14:06:17ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172021-06-0116210611010.5114/pg.2021.10666044280TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel diseaseSara Jarmakiewicz-CzajaAneta SokalJacek TabarkiewiczRafał FilipTiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the ability to accumulate in some internal organs, like spleen, liver, and kidneys, depending on its size and structure. It may have pro-inflammatory, cytotoxic, and genotoxic effects. A change in the composition of the host’s intestinal microflora is also observed after exposure to high doses of TiO2. There are some differences in TiO2 intake with food around the world, but most data indicate higher consumption of this additive by children. Due to the small amount of research and the fact that most of the analyses were carried out using animal models, it is necessary to plan future observations of long-term exposure of the TiO2 molecule.https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.htmltitanium oxide intestinal health. |
spellingShingle | Sara Jarmakiewicz-Czaja Aneta Sokal Jacek Tabarkiewicz Rafał Filip TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease Gastroenterology Review titanium oxide intestinal health. |
title | TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease |
title_full | TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease |
title_fullStr | TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease |
title_full_unstemmed | TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease |
title_short | TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease |
title_sort | tio2 do we have to worry about it one of the important aetiological factors in inflammatory bowel disease |
topic | titanium oxide intestinal health. |
url | https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.html |
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