TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease

TiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the abil...

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Main Authors: Sara Jarmakiewicz-Czaja, Aneta Sokal, Jacek Tabarkiewicz, Rafał Filip
Format: Article
Language:English
Published: Termedia Publishing House 2021-06-01
Series:Gastroenterology Review
Subjects:
Online Access:https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.html
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author Sara Jarmakiewicz-Czaja
Aneta Sokal
Jacek Tabarkiewicz
Rafał Filip
author_facet Sara Jarmakiewicz-Czaja
Aneta Sokal
Jacek Tabarkiewicz
Rafał Filip
author_sort Sara Jarmakiewicz-Czaja
collection DOAJ
description TiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the ability to accumulate in some internal organs, like spleen, liver, and kidneys, depending on its size and structure. It may have pro-inflammatory, cytotoxic, and genotoxic effects. A change in the composition of the host’s intestinal microflora is also observed after exposure to high doses of TiO2. There are some differences in TiO2 intake with food around the world, but most data indicate higher consumption of this additive by children. Due to the small amount of research and the fact that most of the analyses were carried out using animal models, it is necessary to plan future observations of long-term exposure of the TiO2 molecule.
format Article
id doaj-art-5a85848778624e98a60f557e26d77b7c
institution Kabale University
issn 1895-5770
1897-4317
language English
publishDate 2021-06-01
publisher Termedia Publishing House
record_format Article
series Gastroenterology Review
spelling doaj-art-5a85848778624e98a60f557e26d77b7c2025-01-10T14:06:17ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172021-06-0116210611010.5114/pg.2021.10666044280TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel diseaseSara Jarmakiewicz-CzajaAneta SokalJacek TabarkiewiczRafał FilipTiO2 in the food industry, designated as E171, is widely used in the production of chewing gums, sweets, and icing. It is absorbed through food ingestion and the respiratory tract. There are also reports that TiO2 nanoparticles can reach the dermis through damaged epidermis. It demonstrates the ability to accumulate in some internal organs, like spleen, liver, and kidneys, depending on its size and structure. It may have pro-inflammatory, cytotoxic, and genotoxic effects. A change in the composition of the host’s intestinal microflora is also observed after exposure to high doses of TiO2. There are some differences in TiO2 intake with food around the world, but most data indicate higher consumption of this additive by children. Due to the small amount of research and the fact that most of the analyses were carried out using animal models, it is necessary to plan future observations of long-term exposure of the TiO2 molecule.https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.htmltitanium oxide intestinal health.
spellingShingle Sara Jarmakiewicz-Czaja
Aneta Sokal
Jacek Tabarkiewicz
Rafał Filip
TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
Gastroenterology Review
titanium oxide
intestinal
health.
title TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
title_full TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
title_fullStr TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
title_full_unstemmed TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
title_short TiO2 – do we have to worry about it? One of the important aetiological factors in inflammatory bowel disease
title_sort tio2 do we have to worry about it one of the important aetiological factors in inflammatory bowel disease
topic titanium oxide
intestinal
health.
url https://www.termedia.pl/TiO2-do-we-have-to-worry-about-it-One-of-the-important-aetiological-factors-in-inflammatory-bowel-disease,41,44280,1,1.html
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AT jacektabarkiewicz tio2dowehavetoworryaboutitoneoftheimportantaetiologicalfactorsininflammatoryboweldisease
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