The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review

Hypertensive crisis is a medical emergency that requires urgent pharmacological intervention to prevent organ damage. The pathogenesis of this condition is often linked to excessive sympathetic nervous system activation resulting from a strong stress response. Benzodiazepines, as a class of drugs w...

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Main Authors: Łukasz Stojak, Mateusz Grego, Mateusz Baczewski, Dariusz Popiela, Karina Urbańska, Katarzyna Grego, Filip Kwiatkowski, Witold Czyż
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2025-01-01
Series:Quality in Sport
Subjects:
Online Access:https://apcz.umk.pl/QS/article/view/57003
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author Łukasz Stojak
Mateusz Grego
Mateusz Baczewski
Dariusz Popiela
Karina Urbańska
Katarzyna Grego
Filip Kwiatkowski
Witold Czyż
author_facet Łukasz Stojak
Mateusz Grego
Mateusz Baczewski
Dariusz Popiela
Karina Urbańska
Katarzyna Grego
Filip Kwiatkowski
Witold Czyż
author_sort Łukasz Stojak
collection DOAJ
description Hypertensive crisis is a medical emergency that requires urgent pharmacological intervention to prevent organ damage. The pathogenesis of this condition is often linked to excessive sympathetic nervous system activation resulting from a strong stress response. Benzodiazepines, as a class of drugs with anxiolytic and sedative effects mediated through GABA-A receptor modulation, can effectively target the underlying cause of a sudden rise in blood pressure while indirectly contributing to its reduction. This study presents a literature review on the use of benzodiazepines in the treatment of hypertensive crises, with a focus on their mechanisms of action and the limitations associated with their use. The analysis indicates that benzodiazepines, in specific patient groups, can effectively reduce psychological stress and facilitate hemodynamic stabilization. However, the potential risk of adverse effects, such as respiratory depression, must be considered. Benzodiazepines should be used with caution as a therapeutic option in hypertensive crisis management.
format Article
id doaj-art-5a82810a484640f1bde01bde82b7a83a
institution Kabale University
issn 2450-3118
language English
publishDate 2025-01-01
publisher Nicolaus Copernicus University in Toruń
record_format Article
series Quality in Sport
spelling doaj-art-5a82810a484640f1bde01bde82b7a83a2025-01-11T08:22:40ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57003The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature ReviewŁukasz Stojak0https://orcid.org/0009-0008-9910-0445Mateusz Grego1https://orcid.org/0009-0008-4079-2168Mateusz Baczewski2https://orcid.org/0009-0007-2857-5219Dariusz Popiela3https://orcid.org/0009-0009-8648-2365Karina Urbańska4https://orcid.org/0000-0002-1981-9281Katarzyna Grego5https://orcid.org/0009-0005-7388-8885Filip Kwiatkowski6https://orcid.org/0009-0006-3873-1265Witold Czyż7https://orcid.org/0009-0006-4442-990010th military clinical hospital with polyclinic ul. Powstańców Warszawy 5, 85-681 Bydgoszcz, Department of Normal Anatomy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, ul. Łukasiewicza 1, 85-821 Bydgoszcz, Poland10th Military Clinical Hospital with Polyclinic ul. Powstańców Warszawy 5, 85-681 Bydgoszcz, Poland10th military clinical hospital with polyclinic ul. Powstańców Warszawy 5, 85-681 Bydgoszcz, PolandMilitary Institute of Aviation Medicine, Krasińskiego 54/56 Street, 01-755 Warsaw, Poland Central Teaching Hospital of the Medical University of Lodz located at ul. Pomorska 251, 92-213 Lodz, Poland10th Military Clinical Hospital with Polyclinic ul. Powstańców Warszawy 5, 85-681 Bydgoszcz, PolandMilitary Institute of Aviation Medicine, Krasińskiego 54/56 Street, 01-755 Warsaw, Poland Central Teaching Hospital of the Medical University of Lodz located at ul. Pomorska 251, 92-213 Lodz, Poland Hypertensive crisis is a medical emergency that requires urgent pharmacological intervention to prevent organ damage. The pathogenesis of this condition is often linked to excessive sympathetic nervous system activation resulting from a strong stress response. Benzodiazepines, as a class of drugs with anxiolytic and sedative effects mediated through GABA-A receptor modulation, can effectively target the underlying cause of a sudden rise in blood pressure while indirectly contributing to its reduction. This study presents a literature review on the use of benzodiazepines in the treatment of hypertensive crises, with a focus on their mechanisms of action and the limitations associated with their use. The analysis indicates that benzodiazepines, in specific patient groups, can effectively reduce psychological stress and facilitate hemodynamic stabilization. However, the potential risk of adverse effects, such as respiratory depression, must be considered. Benzodiazepines should be used with caution as a therapeutic option in hypertensive crisis management. https://apcz.umk.pl/QS/article/view/57003arterial hypertensionhypertensive crisisbenzodiazepinesblood pressure controlacute hypertension treatment
spellingShingle Łukasz Stojak
Mateusz Grego
Mateusz Baczewski
Dariusz Popiela
Karina Urbańska
Katarzyna Grego
Filip Kwiatkowski
Witold Czyż
The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
Quality in Sport
arterial hypertension
hypertensive crisis
benzodiazepines
blood pressure control
acute hypertension treatment
title The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
title_full The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
title_fullStr The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
title_full_unstemmed The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
title_short The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review
title_sort use of benzodiazepines in the management of hypertensive crisis a literature review
topic arterial hypertension
hypertensive crisis
benzodiazepines
blood pressure control
acute hypertension treatment
url https://apcz.umk.pl/QS/article/view/57003
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