Pulmonary surfactant system
Pulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2) providing a constant essential factor for eas...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=504 |
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| _version_ | 1841561409115127808 |
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| author | Zafer Durgun Ercan Keskin |
| author_facet | Zafer Durgun Ercan Keskin |
| author_sort | Zafer Durgun |
| collection | DOAJ |
| description | Pulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2) providing a constant essential factor for easier pulmonary elastic recoil and reducing the work of breathing during passive expiration; (3) stabilizing the alveoli by lowering the surface tension at the air-liquid interface, or decreasing the tendency of small alveoli to collapse and fuse into larger alveoli at expiration; (4) resisting infiltration of capillary and interstitial fluids into the alveoli; and (5) emulsifying very small inhaled particles that may have reached the alveoli and thus facilitating their phagocytosis by macrophages. lt is stated that deficiencies of surfactant or differences in its composition are concerned with morphofunctional immaturity of lung in prenatal or neonatal period and many pulmonary diseases of adults. Therefore, many investigation are performed on the roles and therapeutic features of surfactant in these diseases and new information is added to old ones in every day. |
| format | Article |
| id | doaj-art-5a6598b3e2d9435a85eae3b6715cddd1 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-5a6598b3e2d9435a85eae3b6715cddd12025-01-03T01:36:53ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531324352504Pulmonary surfactant systemZafer DurgunErcan KeskinPulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2) providing a constant essential factor for easier pulmonary elastic recoil and reducing the work of breathing during passive expiration; (3) stabilizing the alveoli by lowering the surface tension at the air-liquid interface, or decreasing the tendency of small alveoli to collapse and fuse into larger alveoli at expiration; (4) resisting infiltration of capillary and interstitial fluids into the alveoli; and (5) emulsifying very small inhaled particles that may have reached the alveoli and thus facilitating their phagocytosis by macrophages. lt is stated that deficiencies of surfactant or differences in its composition are concerned with morphofunctional immaturity of lung in prenatal or neonatal period and many pulmonary diseases of adults. Therefore, many investigation are performed on the roles and therapeutic features of surfactant in these diseases and new information is added to old ones in every day.http://eurasianjvetsci.org/pdf.php3?id=504pulmonary surfactantsurface tensionhyaline membrane |
| spellingShingle | Zafer Durgun Ercan Keskin Pulmonary surfactant system Eurasian Journal of Veterinary Sciences pulmonary surfactant surface tension hyaline membrane |
| title | Pulmonary surfactant system |
| title_full | Pulmonary surfactant system |
| title_fullStr | Pulmonary surfactant system |
| title_full_unstemmed | Pulmonary surfactant system |
| title_short | Pulmonary surfactant system |
| title_sort | pulmonary surfactant system |
| topic | pulmonary surfactant surface tension hyaline membrane |
| url | http://eurasianjvetsci.org/pdf.php3?id=504 |
| work_keys_str_mv | AT zaferdurgun pulmonarysurfactantsystem AT ercankeskin pulmonarysurfactantsystem |