Power calculation for mosquito bioassays: Quantifying variability in the WHO tube bioassay and developing sample size guidance for the PBO synergism assay using a Shiny application [version 1; peer review: 1 approved, 2 approved with reservations]

Power calculation for mosquito bioassays: Quantifying variability in the WHO tube bioassay and developing sample size guidance for the PBO synergism assay using a Shiny application [version 1; peer review: 1 approved, 2 approved with reservations]

Background The WHO tube bioassay is a method for exposing mosquitos to determine susceptibility to insecticides, with mortality to discriminating doses <98% indicating possible resistance and <90% confirming resistance. This bioassay is also used for synergism testing to assess if susceptibili...

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Bibliographic Details
Main Authors: David Weetman, Jack Gillespie, Giorgio Praulins, Annabel Murphy-Fegan, Frank Mechan, Katherine Gleave, Rosemary Susan Lees, Daniel P. McDermott
Format: Article
Language:English
Published: F1000 Research Ltd 2024-09-01
Series:Gates Open Research
Subjects:
Malaria
vector control
bioassay
mosquito
insecticide resistance
resistance monitoring
eng
Online Access:https://gatesopenresearch.org/articles/8-96/v1
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https://gatesopenresearch.org/articles/8-96/v1

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