Analysis of risk factors for benign central airway stenosis after COVID-19 infection
Abstract Background To investigate the risk factors associated with benign central airway stenosis following COVID-19 infection. Methods The clinical data of 235 patients hospitalized for COVID-19 infection at the First Affiliated Hospital of Zhengzhou University from October 2022 to October 2023 we...
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BMC
2024-12-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-024-02216-5 |
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| author | Ruiyang Wang Jiuling Cheng Yuping Zhang Huaqi Wang |
| author_facet | Ruiyang Wang Jiuling Cheng Yuping Zhang Huaqi Wang |
| author_sort | Ruiyang Wang |
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| description | Abstract Background To investigate the risk factors associated with benign central airway stenosis following COVID-19 infection. Methods The clinical data of 235 patients hospitalized for COVID-19 infection at the First Affiliated Hospital of Zhengzhou University from October 2022 to October 2023 were retrospectively analyzed. Based on the occurrence of postoperative central airway stenosis, the patients were categorized into a stenosis group (118 cases) and a control group (117 cases). The incidence of central airway stenosis following COVID-19 infection was summarized. Univariate and multivariate logistic regression analyses were conducted to identify risk factors associated with central airway stenosis after COVID-19 infection. Results Among the 235 patients studied, 118 developed central airway stenosis. The results of the univariate analysis indicated that age, sex, liver function (as measured by alanine aminotransferase and aspartate aminotransferase values), renal function (creatinine values), diabetes mellitus, fungal airway infections, tuberculosis, and nutritional status (albumin values) were identified as risk factors for benign central airway stenosis following COVID-19 infection (P < 0.05). Furthermore, the multivariate analysis revealed that sex, diabetes mellitus, fungal airway infections, tuberculosis, and nutritional status (albumin values) were independent risk factors for benign central airway stenosis after COVID-19 infection (all P < 0.05). Conclusion diabetes mellitus, fungal airway infections, tuberculosis, and poor nutritional status may lead to benign central airway stenosis after COVID-19 infection. Proactive preventive measures and close monitoring should be taken to improve the quality of life of patients infected with COVID-19. |
| format | Article |
| id | doaj-art-5a55d0cdc6c4416faea79b338d935982 |
| institution | Kabale University |
| issn | 2047-783X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-5a55d0cdc6c4416faea79b338d9359822025-01-12T12:12:55ZengBMCEuropean Journal of Medical Research2047-783X2024-12-012911710.1186/s40001-024-02216-5Analysis of risk factors for benign central airway stenosis after COVID-19 infectionRuiyang Wang0Jiuling Cheng1Yuping Zhang2Huaqi Wang3The First Affiliated Hospital of Zhengzhou UniversityThe First Affiliated Hospital of Zhengzhou UniversityThe First Affiliated Hospital of Zhengzhou UniversityHenan Institute of Interconnected Intelligent Health, Henan Key Laboratory of Chronic Disease Prevention and Therapy & Intelligent Health Management, The First Affiliated Hospital of Zhengzhou UniversityAbstract Background To investigate the risk factors associated with benign central airway stenosis following COVID-19 infection. Methods The clinical data of 235 patients hospitalized for COVID-19 infection at the First Affiliated Hospital of Zhengzhou University from October 2022 to October 2023 were retrospectively analyzed. Based on the occurrence of postoperative central airway stenosis, the patients were categorized into a stenosis group (118 cases) and a control group (117 cases). The incidence of central airway stenosis following COVID-19 infection was summarized. Univariate and multivariate logistic regression analyses were conducted to identify risk factors associated with central airway stenosis after COVID-19 infection. Results Among the 235 patients studied, 118 developed central airway stenosis. The results of the univariate analysis indicated that age, sex, liver function (as measured by alanine aminotransferase and aspartate aminotransferase values), renal function (creatinine values), diabetes mellitus, fungal airway infections, tuberculosis, and nutritional status (albumin values) were identified as risk factors for benign central airway stenosis following COVID-19 infection (P < 0.05). Furthermore, the multivariate analysis revealed that sex, diabetes mellitus, fungal airway infections, tuberculosis, and nutritional status (albumin values) were independent risk factors for benign central airway stenosis after COVID-19 infection (all P < 0.05). Conclusion diabetes mellitus, fungal airway infections, tuberculosis, and poor nutritional status may lead to benign central airway stenosis after COVID-19 infection. Proactive preventive measures and close monitoring should be taken to improve the quality of life of patients infected with COVID-19.https://doi.org/10.1186/s40001-024-02216-5COVID-19 infectionBenign central airway stenosisRisk factorsAlveolar lavage fluidDiabetesFungal infections of the airways |
| spellingShingle | Ruiyang Wang Jiuling Cheng Yuping Zhang Huaqi Wang Analysis of risk factors for benign central airway stenosis after COVID-19 infection European Journal of Medical Research COVID-19 infection Benign central airway stenosis Risk factors Alveolar lavage fluid Diabetes Fungal infections of the airways |
| title | Analysis of risk factors for benign central airway stenosis after COVID-19 infection |
| title_full | Analysis of risk factors for benign central airway stenosis after COVID-19 infection |
| title_fullStr | Analysis of risk factors for benign central airway stenosis after COVID-19 infection |
| title_full_unstemmed | Analysis of risk factors for benign central airway stenosis after COVID-19 infection |
| title_short | Analysis of risk factors for benign central airway stenosis after COVID-19 infection |
| title_sort | analysis of risk factors for benign central airway stenosis after covid 19 infection |
| topic | COVID-19 infection Benign central airway stenosis Risk factors Alveolar lavage fluid Diabetes Fungal infections of the airways |
| url | https://doi.org/10.1186/s40001-024-02216-5 |
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