Detecting the Major Degradation Products of Phosphorothioate Oligonucleotides by Chemical Derivatization and Weak Anion Exchange Chromatography

Detecting the Major Degradation Products of Phosphorothioate Oligonucleotides by Chemical Derivatization and Weak Anion Exchange Chromatography

Saved in:

Bibliographic Details
Main Authors:	Stilianos G. Roussis, Christopher M. Gabriel, Andrew A. Rodriguez, Claus Rentel
Format:	Article
Language:	English
Published:	American Chemical Society 2024-11-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.4c08543
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Molecularly Imprinted Nanomicrospheres as Matrix Solid-Phase Dispersant Combined with Gas Chromatography for Determination of Four Phosphorothioate Pesticides in Carrot and Yacon
by: Mengchun Zhou, et al.
Published: (2015-01-01)

Determination of Curdlan Oligosaccharides with High-Performance Anion Exchange Chromatography with Pulsed Amperometric Detection
by: Lidong Cao, et al.
Published: (2018-01-01)

Determination of Amino Acid Composition of Cow’s Milk by LiquidChromatography Using Precolumn Derivatization
by: A. Mazhitova, et al.
Published: (2017-12-01)

Analysis of inorganic arsenic and methylarsenic in soil after derivatization by gas chromatography-mass spectrometry.
by: Wenzhi Zhao, et al.
Published: (2024-01-01)

Analytical Method Development for Sodium Valproate through Chemical Derivatization
by: Murad Abualhasan, et al.
Published: (2020-01-01)

Anion-Exchange Membranes’ Characteristics and Catalysts for Alkaline Anion-Exchange Membrane Fuel Cells
by: Fa-Cheng Su, et al.
Published: (2024-11-01)

Fast and reliable method for analysis of derivatized plasma amino acids by liquid chromatography-single quadrupole-mass spectrometry
by: August Hoppmann, et al.
Published: (2024-11-01)

Derivatization of Levoglucosan for Compound-Specific δ13C Analysis by Gas Chromatography/Combustion/Isotope Ratio Mass Spectrometry
by: Dongling Zhang, et al.
Published: (2020-01-01)

Removal of 2-naphthalenesulfonic acid using novel dual functional weakly basic anion exchange resins from aqueous solution
by: Yue Sun, et al.
Published: (2019-05-01)

Rapid and convenient determination of α-dicarbonyl compounds via streamlined simultaneous derivatization and extraction coupled with liquid chromatography-fluorescence detection
by: Yanbo Luo, et al.
Published: (2024-12-01)

Analysis of diclofenac in water samples using in situ derivatization-vortex-assisted liquid-liquid microextraction with gas chromatography-mass spectrometry
by: Aydin Senar, et al.
Published: (2018-09-01)

Studies of the Sorption of Palladium(II) Ions from Model Chloride Systems onto an Ion Exchanger Containing Isothiourea Groups and onto Weakly Basic Anion Exchangers of Various Types
by: Z. Hubicki, et al.
Published: (2004-09-01)

Water-mediated ion transport in an anion exchange membrane
by: Zhongyang Wang, et al.
Published: (2025-01-01)

Phthalylglycyl chloride as a derivatization reagent for determination of urinary amino acids using ultra high-performance liquid chromatography coupled with high resolution mass spectrometry
by: Azamat Temerdashev, et al.
Published: (2024-11-01)

Fluorescent Thiol-Derivatized Gold Clusters Embedded in Polymers
by: G. Carotenuto, et al.
Published: (2013-01-01)

Ion-pair reversed-phase chromatography analysis of oligonucleotides using ultra-short (20 x 2.1 mm) columns. Tutorial
by: Szabolcs Fekete, et al.
Published: (2024-11-01)

Degradation of aflatoxins in weakly alkaline conditions
by: Natalie Sandlin, et al.
Published: (2025-01-01)

Removal of Hexavalent Chromium Ions from Aqueous Solutions by an Anion-Exchange Resin
by: P. Senthil Kumar, et al.
Published: (2008-11-01)

Evaluation of anion exchange resin for sorption of selenium (IV) from aqueous solutions
by: A. El-Tantawy, et al.
Published: (2025-01-01)

Effect of the flow field structures on the performance of anion exchange membrane water electrolyzer
by: Rui DING, et al.
Published: (2024-12-01)

Adsorption Properties of Ni(II) by D301R Anion Exchange Resin
by: Song Xiuling, et al.
Published: (2014-01-01)

Parameter Analysis of Anion Exchange Membrane Water Electrolysis System by Numerical Simulation
by: Shing-Cheng Chang, et al.
Published: (2024-11-01)

Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform
by: Tommaso Tabaglio, et al.
Published: (2025-03-01)

Determination of 13 Aminoglycoside Residues in Milk by Weak Cation Exchange Solid Phase Extraction Coupled with Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry
by: HE Jinlin, SHEN Luying, SUN Ting, FU Jianwei, YAN Lijuan, XU Dunming
Published: (2025-02-01)

Tofersen and other antisense oligonucleotides in ALS
by: Albert Ludolph, et al.
Published: (2025-01-01)

Enhanced Performance and Durability of Pore-Filling Membranes for Anion Exchange Membrane Water Electrolysis
by: Minyoung Lee, et al.
Published: (2024-12-01)

Preparation and characterization of graphene oxide-based cation, chelating, and anion exchangers for salt removal
by: Mahmoud A. Al Azwani, et al.
Published: (2025-02-01)

Synthesis and Physicochemical Characterization of Anion Exchanger Based on Green Modified Bottle Gourd Shell
by: Dragana Z. Marković-Nikolić, et al.
Published: (2018-01-01)

A tutorial on solid-phase analytical derivatization in sample preparation applications
by: Azamat Temerdashev, et al.
Published: (2024-11-01)

Investigating Flavonoids by HPTLC Analysis Using Aluminium Chloride as Derivatization Reagent
by: Sharmin Sultana, et al.
Published: (2024-10-01)

Protocol for the synthesis and activation of hydrogels with photocaged oligonucleotides
by: Danielle Herubin, et al.
Published: (2025-03-01)

Functionalized oligonucleotides, synthetic catalysts as enzyme mimics
by: Chardet, Crystalle, et al.
Published: (2024-04-01)

Amphiphilic Oligonucleotide Derivatives—Promising Tools for Therapeutics
by: Irina A. Bauer, et al.
Published: (2024-11-01)

Heavy Metal Ion Removal Characteristics of Monodisperse Macroporous Beads with Anion-Exchanger Molecular Brushes
by: Hülya Yavuz Ersan, et al.
Published: (2011-09-01)

Alkaline Hydrogen Evolution Reaction Electrocatalysts for Anion Exchange Membrane Water Electrolyzers: Progress and Perspective
by: Yiming Zhu, et al.
Published: (2024-11-01)

Recent advances in anion exchange membrane technology for water electrolysis: a review of progress and challenges
by: Abdul Qayoom, et al.
Published: (2024-11-01)

Development of a Reliable Analytical Method for Liquid Anion-Exchange Extraction and Separation of Neodymium(III)
by: Balasaheb N. Kokare, et al.
Published: (2012-01-01)

Preparation of Two-Layer Anion-Exchange Poly(ethersulfone) Based Membrane: Effect of Surface Modification
by: Lucie Zarybnicka, et al.
Published: (2016-01-01)

Synthesis and Properties of Anion Exchangers Derived from Chloromethyl Styrene Codivinylbenzene and Their Use in Water Treatment
by: Hesham A. Ezzeldin, et al.
Published: (2010-01-01)

MXene-Assisted NiFe sulfides for high-performance anion exchange membrane seawater electrolysis
by: Jiaqi Wang, et al.
Published: (2025-02-01)