The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study
ABSTRACT Background and Aim This study aims to compare the mortality rate, length of stay (LOS), and hospitalization cost in patients with and without healthcare‐associated infections (HCAIs). Methods This prospective cohort study is conducted on 396 matched patients admitted to a tertiary teaching...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-11-01
|
| Series: | Health Science Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/hsr2.70168 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846151685209063424 |
|---|---|
| author | Samaneh Moradi Zhila Najafpour Bahman Cheraghian Iman Keliddar Razieh Mombeyni |
| author_facet | Samaneh Moradi Zhila Najafpour Bahman Cheraghian Iman Keliddar Razieh Mombeyni |
| author_sort | Samaneh Moradi |
| collection | DOAJ |
| description | ABSTRACT Background and Aim This study aims to compare the mortality rate, length of stay (LOS), and hospitalization cost in patients with and without healthcare‐associated infections (HCAIs). Methods This prospective cohort study is conducted on 396 matched patients admitted to a tertiary teaching hospital with 800 beds in the southwest of Iran from July 2021 to January 2022. The cases were patients admitted during the study period who had, at minimum, one type of HCAI. For a comparison group, we considered all patients without HCAIs who hospitalized in the same ward and at the same time with the same age and gender in a ratio of one case to three controls. Descriptive analyses were done based on direct medical costs, LOS, and mortality rate in patients. The magnitude of the relationship between potential risk factors and HCAI was quantified using logistic regression. Results The most common HCAI and microorganisms were urinary tract infection (UTI) and Escherichia coli, respectively. The mean LOS for infected patients was 20.3 (±16) days, compared to 8.7 (±8.6) days for noninfected patients (p value ≤ 0.05). Lengths of stay (odds ratio [OR] = 1.09; 95% CI = 1.06–1.19; p value = 0.000), ICU lengths of stay (OR = 1.08; 95% CI = 1.02–1.15; p value = 0.003), presence of central Catheter (OR = 0.127; 95% CI = 0.51–0.319; p value = 0.000), and urinary catheter (OR = 0.225; 95% CI = 0.122–0.415; p value = 0.000), mechanical ventilation (OR = 0.136; 95% CI = 0.57–0.325; p value = 0.000), receipt of immunosuppressors (OR = 1.99; 95% CI = 11.12–3.56; p value = 0.01), were Significantly associated with HCAI. Patients with infections had a more costly hospital stay than noninfected patients (mean diff: $2037.46 ([SD]: 482.25$) (p value = 0.000). The highest cost component was the cost of medication expenditure (mean: $1612.66 ([SD]: $2542.27). Conclusions UTI was the most common HCAI in our study. An infection acquired during a hospital stay may be associated with higher hospitalization costs, prolonged hospitalization, and an increase in the rate of mortality. Longer lengths of stay, presence of central and urinary Catheters, receipt of immunosuppressors, use of mechanical ventilator were common risk factors for HCAI. This study reveals that the median reimbursement cost per hospitalization of patients with HCAIs was higher than patients without HCAIs. This highlights the necessity for implementation of HCAI prevention and control measures. |
| format | Article |
| id | doaj-art-5a000b3ea40a484db38ccad8f3080f1a |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj-art-5a000b3ea40a484db38ccad8f3080f1a2024-11-27T05:20:45ZengWileyHealth Science Reports2398-88352024-11-01711n/an/a10.1002/hsr2.70168The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control StudySamaneh Moradi0Zhila Najafpour1Bahman Cheraghian2Iman Keliddar3Razieh Mombeyni4Department of Health Care Management, School of Public Health Ahvaz Jundishapur University of Medical Sciences Ahvaz IranDepartment of Health Care Management, School of Public Health Ahvaz Jundishapur University of Medical Sciences Ahvaz IranDepartment of Biostatistics and Epidemiology, School of Public Health Ahvaz Jundishapur University of Medical Sciences Ahvaz IranDepartment of Health Care Management, School of Public Health Ahvaz Jundishapur University of Medical Sciences Ahvaz IranSchool of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz IranABSTRACT Background and Aim This study aims to compare the mortality rate, length of stay (LOS), and hospitalization cost in patients with and without healthcare‐associated infections (HCAIs). Methods This prospective cohort study is conducted on 396 matched patients admitted to a tertiary teaching hospital with 800 beds in the southwest of Iran from July 2021 to January 2022. The cases were patients admitted during the study period who had, at minimum, one type of HCAI. For a comparison group, we considered all patients without HCAIs who hospitalized in the same ward and at the same time with the same age and gender in a ratio of one case to three controls. Descriptive analyses were done based on direct medical costs, LOS, and mortality rate in patients. The magnitude of the relationship between potential risk factors and HCAI was quantified using logistic regression. Results The most common HCAI and microorganisms were urinary tract infection (UTI) and Escherichia coli, respectively. The mean LOS for infected patients was 20.3 (±16) days, compared to 8.7 (±8.6) days for noninfected patients (p value ≤ 0.05). Lengths of stay (odds ratio [OR] = 1.09; 95% CI = 1.06–1.19; p value = 0.000), ICU lengths of stay (OR = 1.08; 95% CI = 1.02–1.15; p value = 0.003), presence of central Catheter (OR = 0.127; 95% CI = 0.51–0.319; p value = 0.000), and urinary catheter (OR = 0.225; 95% CI = 0.122–0.415; p value = 0.000), mechanical ventilation (OR = 0.136; 95% CI = 0.57–0.325; p value = 0.000), receipt of immunosuppressors (OR = 1.99; 95% CI = 11.12–3.56; p value = 0.01), were Significantly associated with HCAI. Patients with infections had a more costly hospital stay than noninfected patients (mean diff: $2037.46 ([SD]: 482.25$) (p value = 0.000). The highest cost component was the cost of medication expenditure (mean: $1612.66 ([SD]: $2542.27). Conclusions UTI was the most common HCAI in our study. An infection acquired during a hospital stay may be associated with higher hospitalization costs, prolonged hospitalization, and an increase in the rate of mortality. Longer lengths of stay, presence of central and urinary Catheters, receipt of immunosuppressors, use of mechanical ventilator were common risk factors for HCAI. This study reveals that the median reimbursement cost per hospitalization of patients with HCAIs was higher than patients without HCAIs. This highlights the necessity for implementation of HCAI prevention and control measures.https://doi.org/10.1002/hsr2.70168case‐control studycostshealthcare‐associated infectionslength of staymortality |
| spellingShingle | Samaneh Moradi Zhila Najafpour Bahman Cheraghian Iman Keliddar Razieh Mombeyni The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study Health Science Reports case‐control study costs healthcare‐associated infections length of stay mortality |
| title | The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study |
| title_full | The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study |
| title_fullStr | The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study |
| title_full_unstemmed | The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study |
| title_short | The Extra Length of Stay, Costs, and Mortality Associated With Healthcare‐Associated Infections: A Case‐Control Study |
| title_sort | extra length of stay costs and mortality associated with healthcare associated infections a case control study |
| topic | case‐control study costs healthcare‐associated infections length of stay mortality |
| url | https://doi.org/10.1002/hsr2.70168 |
| work_keys_str_mv | AT samanehmoradi theextralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT zhilanajafpour theextralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT bahmancheraghian theextralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT imankeliddar theextralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT raziehmombeyni theextralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT samanehmoradi extralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT zhilanajafpour extralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT bahmancheraghian extralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT imankeliddar extralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy AT raziehmombeyni extralengthofstaycostsandmortalityassociatedwithhealthcareassociatedinfectionsacasecontrolstudy |